Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055571426> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2055571426 endingPage "802" @default.
- W2055571426 startingPage "795" @default.
- W2055571426 abstract "Radioisotopes and t.l.c. were used to indirectly determine the distribution and proportions of Vitamin A compounds in the rat eye. In the dark adapted eye there are Vitamin A compounds in the pigment epithelium; these compounds are likely within the rod outer segment discs being digested there. During light adaptation. 11-cis retinal decreases, alltrans retinal increases and is reduced to retinol, and retinol is esterified to fatty acids in the retina and in the pigment epithelium. Essentially the reverse occurs during dark adaptation. It is suggested that the metabolism of Vitamin A compounds in the eye functions to return chromophore to the newly synthesized visual pigment at the base of the rod outer segment. On emploie les radioisotopes et la chromatographie en couche mince pour déterminer indirectement la distribution et les proportions des composés de Vitamine A dans l'oeil du rat. Dans l'oeil adaptéàl'obscurité, il y a des composés de Vitamine A dans l'épithélium pigmentaire; il est probable que ces composés sont utilisés dans les disques des segments externes des baˆtonnets. En adaptationàla lumière, le rétinal 11-cis décroit, tout le rétinaltrans augmente et est réduit en rétinol, et le rétinol est estérifiéen acides gras dans la rétine et dans l'épithélium pigmentaire. En gros l'inverse se passe en adaptationàl'obscurité. On suggère que le métabolisme des composés de Vitamine A dans l'oeil sertàrétablir le chromophore dans le pigment visuel synthétiséànouveauàla base de segment externe du baˆtonnet. Radioisotopie und Dünnschichtchromatographie wurden zum indirekten Nachweis von Verteilung und Häufigkeit von Vitamin-A-Verbindungen im Rattenauge verwendet. Im dunkeladaptierten Auge enthält das Pigmentepithel Vitamin-A-Verbindungen; diese Verbindungen befinden sich wahrscheinlich in denäusseren Stäbchensegmentscheiben in gelöstem Zustand. Bei Helladaptation nimmt 11′-cis-Retinen ab und all-trans-Retinen zu und wird zu Retinol reduziert. Dieses verestert zu Fettsäure in der Retina und im Pigmentepithel. Im wesentlichen das Umgekehrte geschieht bei Dunkeladaptation. Es wird vermutet, dass der Metabolismus der Vitamin-A-Verbindungen im Auge so wirkt, dass die chromophore Gruppe zu dem erneut erzeugten Sehpigment an der Basis desäusseren Stäbchensegmentes zurückwandert. Paдиoизoтoпы и тoнкo-cлoйнaя хpoмaтoгpaфия были иcпoльзoвaны для нeпpямoгo oпpeдeлeния pacпpeдeлeния и пpoпopций coeдинeний витaминa A в глaзy кpыcы. B тeмнoaдaптиpoвaннoм глaзy coeдинeния нaхoдятcя в пигмeнтнoм зпитeлии; зти coeдинeния, вepoятн, ycвaивaютcя внyтpи диcкoв нapyжных ceгмeнтoв пaлoхeк. Bo вpeмя cвeтoвoй aдaптaции, coдepжaниe 11-хИc peтинaля-yвeИхИвaвTcя и oн вoccтaнaaливaeтcя дo peтинoлa, и peтинoл зкcтpифициpyeтcя дo жиpных киcлoт в ceтхaткe и пигмeнтнoм зпитeлии. Cyщceтвeннo, хтo oбpaтнaя peaкция нaблюдaeтcя вo вpeмя тeмнoвoй aдaптaции. Пpeдиoлoжeнo, хтo мeтaбoлизм coeдинeний витaминa A в глaзy paбoтaeт, хтoбы вepнyть хpoмoфop к внoвь cинтeзиpyющeмycя зpитeльнoмy пигмeнтy в ocнoвaнии нapyжнoгo ceгмeнтa пaлoхки." @default.
- W2055571426 created "2016-06-24" @default.
- W2055571426 creator A5012160499 @default.
- W2055571426 date "1974-09-01" @default.
- W2055571426 modified "2023-10-18" @default.
- W2055571426 title "The distribution and proportions of vitamin A compounds during the visual cycle in the rat" @default.
- W2055571426 cites W1541765040 @default.
- W2055571426 cites W1969358879 @default.
- W2055571426 cites W1984946513 @default.
- W2055571426 cites W1992632065 @default.
- W2055571426 cites W1994535916 @default.
- W2055571426 cites W1996961162 @default.
- W2055571426 cites W2017494946 @default.
- W2055571426 cites W2023854062 @default.
- W2055571426 cites W2073852168 @default.
- W2055571426 cites W2086790354 @default.
- W2055571426 cites W2091032730 @default.
- W2055571426 cites W2200435831 @default.
- W2055571426 cites W2324029345 @default.
- W2055571426 cites W2331585727 @default.
- W2055571426 cites W82274121 @default.
- W2055571426 cites W98911922 @default.
- W2055571426 doi "https://doi.org/10.1016/0042-6989(74)90143-6" @default.
- W2055571426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4418913" @default.
- W2055571426 hasPublicationYear "1974" @default.
- W2055571426 type Work @default.
- W2055571426 sameAs 2055571426 @default.
- W2055571426 citedByCount "125" @default.
- W2055571426 countsByYear W20555714262013 @default.
- W2055571426 countsByYear W20555714262014 @default.
- W2055571426 countsByYear W20555714262015 @default.
- W2055571426 countsByYear W20555714262018 @default.
- W2055571426 crossrefType "journal-article" @default.
- W2055571426 hasAuthorship W2055571426A5012160499 @default.
- W2055571426 hasConcept C153911025 @default.
- W2055571426 hasConcept C178790620 @default.
- W2055571426 hasConcept C185592680 @default.
- W2055571426 hasConcept C2776940978 @default.
- W2055571426 hasConcept C2778024200 @default.
- W2055571426 hasConcept C2779573558 @default.
- W2055571426 hasConcept C2780827179 @default.
- W2055571426 hasConcept C55493867 @default.
- W2055571426 hasConcept C64584667 @default.
- W2055571426 hasConcept C71240020 @default.
- W2055571426 hasConcept C86803240 @default.
- W2055571426 hasConceptScore W2055571426C153911025 @default.
- W2055571426 hasConceptScore W2055571426C178790620 @default.
- W2055571426 hasConceptScore W2055571426C185592680 @default.
- W2055571426 hasConceptScore W2055571426C2776940978 @default.
- W2055571426 hasConceptScore W2055571426C2778024200 @default.
- W2055571426 hasConceptScore W2055571426C2779573558 @default.
- W2055571426 hasConceptScore W2055571426C2780827179 @default.
- W2055571426 hasConceptScore W2055571426C55493867 @default.
- W2055571426 hasConceptScore W2055571426C64584667 @default.
- W2055571426 hasConceptScore W2055571426C71240020 @default.
- W2055571426 hasConceptScore W2055571426C86803240 @default.
- W2055571426 hasIssue "9" @default.
- W2055571426 hasLocation W20555714261 @default.
- W2055571426 hasLocation W20555714262 @default.
- W2055571426 hasOpenAccess W2055571426 @default.
- W2055571426 hasPrimaryLocation W20555714261 @default.
- W2055571426 hasRelatedWork W108060262 @default.
- W2055571426 hasRelatedWork W1144875082 @default.
- W2055571426 hasRelatedWork W1985701617 @default.
- W2055571426 hasRelatedWork W200621325 @default.
- W2055571426 hasRelatedWork W2011386178 @default.
- W2055571426 hasRelatedWork W2018042440 @default.
- W2055571426 hasRelatedWork W2059466813 @default.
- W2055571426 hasRelatedWork W3022926771 @default.
- W2055571426 hasRelatedWork W4234043206 @default.
- W2055571426 hasRelatedWork W885671680 @default.
- W2055571426 hasVolume "14" @default.
- W2055571426 isParatext "false" @default.
- W2055571426 isRetracted "false" @default.
- W2055571426 magId "2055571426" @default.
- W2055571426 workType "article" @default.