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- W2055656928 abstract "s1 May 1965The American College of Physicians Honorary Fellowship Lecture: Coronary Thrombosis: Its Mechanism and Possible Prevention by Linolenic Acid.Paul A. Owren, F.A.C.P.Paul A. Owren, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-1068_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSecondary thrombosis has an important role in the clinical course of coronary atherosclerotic disease. The initial reactions in thrombus formation include: (1) Adhesion of blood platelets to damaged endothelium and to collagen fibres, (2) release of adenosine diphosphate (ADP) by contact of platelets with collagen, and (3) reversible platelet aggregation in the presence of ADP, calcium, and the anti-Willebrand factor (the bleeding factor lacking in von Willebrand's disease). All these reactions are independent on the blood coagulation systems.No general factors are known that influence the two first reactions. The third reaction, which produces loose platelet thrombi, is largely determined... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Paul A. Owren, F.A.C.P.Affiliations: Oslo, PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1965Volume 62, Issue 5Page: 1068-1069KeywordsAdenosine diphosphateCalciumEndotheliumFellowshipsHemorrhagePlatelet aggregationPlateletsStable coronary artery diseaseThrombosisvon Willebrand disease ePublished: 1 December 2008 Issue Published: 1 May 1965 PDF downloadLoading ..." @default.
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- W2055656928 title "The American College of Physicians Honorary Fellowship Lecture: Coronary Thrombosis: Its Mechanism and Possible Prevention by Linolenic Acid." @default.
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