Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055711558> ?p ?o ?g. }
- W2055711558 endingPage "34" @default.
- W2055711558 startingPage "19" @default.
- W2055711558 abstract "Pain normally serves as a warning and protective signal and is important for the survival of animals and humans. However, chronic neuropathic pain causes excruciating suffering that disrupts the quality of patients' lives. Chronic neuropathic pain remains a significant health problem because it is often resistant to conventional analgesics. Central sensitization is a common feature of neuropathic pain, but the cellular and molecular mechanisms underlying the abnormal sensory processing in neuropathic pain are not fully understood. In this article, we reviewed the efficacy and pharmacological actions of several classes of drugs, including opioids, antidepressants, anticonvulsants, and NMDA receptor antagonists, currently used to treat neuropathic pain in patients and animal models. Recent studies have provided substantial new information on the analgesic mechanisms of these drugs. We also have presented a critical review on current understanding of the pharmacological actions of commonly used analgesics for neuropathic pain treatment. Neuropathic pain with different etiologies likely requires different treatment strategies. Thus, patients with neuropathic pain should be examined using a comprehensive and integrated approach, and an individualized, mechanism-based treatment is needed to satisfactorily manage refractory neuropathic pain." @default.
- W2055711558 created "2016-06-24" @default.
- W2055711558 creator A5004263546 @default.
- W2055711558 creator A5085520556 @default.
- W2055711558 date "2006-04-18" @default.
- W2055711558 modified "2023-10-16" @default.
- W2055711558 title "An Update on Pharmacological Actions of Drugs for Neuropathic Pain Treatment" @default.
- W2055711558 cites W1536330210 @default.
- W2055711558 cites W1565438915 @default.
- W2055711558 cites W1567615855 @default.
- W2055711558 cites W1572285252 @default.
- W2055711558 cites W1575571855 @default.
- W2055711558 cites W160855862 @default.
- W2055711558 cites W1799894364 @default.
- W2055711558 cites W1939163692 @default.
- W2055711558 cites W1951343274 @default.
- W2055711558 cites W1954411904 @default.
- W2055711558 cites W1963819476 @default.
- W2055711558 cites W1964551789 @default.
- W2055711558 cites W1964575045 @default.
- W2055711558 cites W1966133272 @default.
- W2055711558 cites W1967053379 @default.
- W2055711558 cites W1968535715 @default.
- W2055711558 cites W1968984411 @default.
- W2055711558 cites W1972721493 @default.
- W2055711558 cites W1972856190 @default.
- W2055711558 cites W1975185129 @default.
- W2055711558 cites W1975275982 @default.
- W2055711558 cites W1975313037 @default.
- W2055711558 cites W1976087780 @default.
- W2055711558 cites W1976166428 @default.
- W2055711558 cites W1976712777 @default.
- W2055711558 cites W1978174847 @default.
- W2055711558 cites W1979145649 @default.
- W2055711558 cites W1979744318 @default.
- W2055711558 cites W1981468043 @default.
- W2055711558 cites W1981624978 @default.
- W2055711558 cites W1984279115 @default.
- W2055711558 cites W1984377108 @default.
- W2055711558 cites W1986528681 @default.
- W2055711558 cites W1986849239 @default.
- W2055711558 cites W1988059170 @default.
- W2055711558 cites W1988651635 @default.
- W2055711558 cites W1989235554 @default.
- W2055711558 cites W1989804049 @default.
- W2055711558 cites W1990817401 @default.
- W2055711558 cites W1991550485 @default.
- W2055711558 cites W1992208902 @default.
- W2055711558 cites W1993697980 @default.
- W2055711558 cites W1995796629 @default.
- W2055711558 cites W1996195482 @default.
- W2055711558 cites W1998165780 @default.
- W2055711558 cites W1998167985 @default.
- W2055711558 cites W1998320018 @default.
- W2055711558 cites W2001423085 @default.
- W2055711558 cites W2002863542 @default.
- W2055711558 cites W2004035928 @default.
- W2055711558 cites W2004617102 @default.
- W2055711558 cites W2005022730 @default.
- W2055711558 cites W2008342377 @default.
- W2055711558 cites W2008609792 @default.
- W2055711558 cites W2009185989 @default.
- W2055711558 cites W2009979296 @default.
- W2055711558 cites W2010424991 @default.
- W2055711558 cites W2011041937 @default.
- W2055711558 cites W2011831455 @default.
- W2055711558 cites W2013164405 @default.
- W2055711558 cites W2014765305 @default.
- W2055711558 cites W2016958489 @default.
- W2055711558 cites W2017549423 @default.
- W2055711558 cites W2017756102 @default.
- W2055711558 cites W2017836712 @default.
- W2055711558 cites W2018670263 @default.
- W2055711558 cites W2020820202 @default.
- W2055711558 cites W2022302423 @default.
- W2055711558 cites W2023374499 @default.
- W2055711558 cites W2024818305 @default.
- W2055711558 cites W2025235669 @default.
- W2055711558 cites W2025416476 @default.
- W2055711558 cites W2025794199 @default.
- W2055711558 cites W2027520560 @default.
- W2055711558 cites W2028111627 @default.
- W2055711558 cites W2028243509 @default.
- W2055711558 cites W2032034626 @default.
- W2055711558 cites W2035781193 @default.
- W2055711558 cites W2036207561 @default.
- W2055711558 cites W2036266410 @default.
- W2055711558 cites W2036761672 @default.
- W2055711558 cites W2037709765 @default.
- W2055711558 cites W2039982019 @default.
- W2055711558 cites W2040059440 @default.
- W2055711558 cites W2040472450 @default.
- W2055711558 cites W2040621685 @default.
- W2055711558 cites W2041369808 @default.
- W2055711558 cites W2043487642 @default.
- W2055711558 cites W2045232188 @default.
- W2055711558 cites W2047630289 @default.
- W2055711558 cites W2048055029 @default.