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- W2055731999 abstract "The effect of bonito insulin on insulin release was examined in the monolayer culture of rat pancreatic beta-cells. The beta-cells were preincubated for 5 to 20 hr with or without a small dose (100 microunits/ml) of bonito insulin in the medium containing 100 mg% glucose. And then, they were incubated in 300 mg% glucose alone or together with bonito insulin for 5 hr. There was no significant difference between the IRI release from these beta-cells with or without bonito insulin. The concentration of bonito insulin was augmented from 100 microunits/ml to 500, 1,000 and 2,000 microunits/ml. A significant inhibitory effect on the glucose-induced insulin release was observed only after the preincubation for 20 hr with 2,000 microunits/ml of bonito insulin." @default.
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- W2055731999 date "1978-01-01" @default.
- W2055731999 modified "2023-10-03" @default.
- W2055731999 title "Effect of the bonito insulin on the insulin release from monolayer culture of rat pancreas." @default.
- W2055731999 doi "https://doi.org/10.1507/endocrj1954.25.443" @default.
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