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- W2055759166 abstract "A biomarker may be defined as ‘‘a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention’’. When assessing the need for a biomarker in clinical practice, a crucial aspect of its value is whether it might improve patient management. In this regard, biomarkers may provide important information regarding the presence, severity, and prognosis of specific disease processes, and may also provide important information regarding management options; such information may not be clinically obvious without biomarker measurement. As such, biomarkers are increasingly of interest for use in critical care medicine, for the early recognition of organ injury and to better understand the pathological processes leading to organ failure. Because of both the high prevalence and the poor prognosis associated with acute kidney injury (AKI) and with cardiovascular failure in the critically ill, this paper describes new findings in the critical care application of renal and cardiovascular biomarkers (Table 1)." @default.
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- W2055759166 date "2013-07-05" @default.
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- W2055759166 title "Critical research on biomarkers: what’s new?" @default.
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- W2055759166 doi "https://doi.org/10.1007/s00134-013-3008-7" @default.
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