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• W2055815582 abstract "Several surface active small molecules induce an unusual phase in dipalmitoylphosphatidylcholine (DPPC) suspensions. In this phase, the lipid hydrocarbon chains from apposing monolayers interpenetrate or interdigitate. A structural analysis by X-ray diffraction shows that with incorporation of the drug chlorpromazine, the bilayer thickness, or lipid headgroup separation, in DPPC liposomes is only 30 Å, which is about 20 Å smaller than two fully-extended DPPC molecules. This interdigitated phase may be a more general phenomenon than previously believed, as several other molecules, both charged and uncharged, such as tetracaine and benzyl alcohol, can cause the lipid hydrocarbon chains to interpenetrate." @default.
• W2055815582 created "2016-06-24" @default.
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• W2055815582 date "1983-05-01" @default.
• W2055815582 modified "2023-09-24" @default.
• W2055815582 title "Induction of an interdigitated gel phase in fully hydrated phosphatidylcholine bilayers" @default.
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• W2055815582 doi "https://doi.org/10.1016/0005-2736(83)90403-0" @default.
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