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- W2055820181 abstract "A β-oxidative cleavage of oleyl- and stearyl-CoA has been obtained with soluble enzymes of rat-liver homogenate. The transformation requires NAD+ as an oxido-reductive cofactor and is enhanced by ATP and CoA. Under the reported conditions 2,9-octadecadienoic, 3,9-octadecadienoic, 3-hydroxy-9-octadecenoic, 7-hexadecenoic, 3-hydroxy-7-hexadecenoic and 5-tetradecenoic acids are present after incubation of oleyl-CoA, while no detectable amounts of shorter fatty acids are formed. A similar oxidation pattern is obtained with stearyl-CoA when Mg2+ ions are also added to the system. The cytoplasmic origin of these enzymes is established by comparing their activity with that of the mitochondrial β-oxidation enzymes." @default.
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- W2055820181 date "1973-10-01" @default.
- W2055820181 modified "2023-09-27" @default.
- W2055820181 title "The beta-Oxidative Cleavage of Long-Chain Fatty Acids in Rat-Liver Cytoplasm" @default.
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- W2055820181 doi "https://doi.org/10.1111/j.1432-1033.1973.tb03087.x" @default.
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