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- W2055837112 abstract "We investigated the effect of Lactobacillus crispatus KT-11 (KT-11) on intestinal immune systems in C3H/HeN mice. The level of intestinal total immunoglobulin (Ig) A was significantly higher in mice given KT-11 than in mice not given KT-11. Gene expression relating to antibody production and innate immune response increased more than 2-fold in the former compared with the later. Moreover, the number of IL-6+CD11b+ cells was significantly higher in Peyer's patch cells cultured with KT-11 than in those cultured without KT-11, although the number of CD4+ cells and the cell ratio of CD4+/CD8+ were remarkably lower in the culture with KT-11. These results indicate that KT-11 enhances intestinal IgA production and innate immune response in C3H/HeN mice." @default.
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- W2055837112 date "2010-01-01" @default.
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- W2055837112 title "Lactobacillus crispatus KT-11 Enhances Intestinal Immune Functions in C3H/HeN Mice" @default.
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- W2055837112 doi "https://doi.org/10.3177/jnsv.56.441" @default.
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