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• W2055872765 abstract "A dramatic acceleration of the enantioselective copper-catalyzed conjugate reduction of alpha,beta-unsaturated lactones, lactams, and esters is reported upon addition of alcohol additives. Good to excellent yields and enantioselectivities were realized using a catalyst generated in situ from CuCl(2).H(2)O, t-BuONa, p-tol-BINAP, and PMHS, and this methodology was applied to the synthesis of (-)-Paroxetine." @default.
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• W2055872765 date "2003-08-19" @default.
• W2055872765 modified "2023-10-18" @default.
• W2055872765 title "Catalytic Enantioselective Conjugate Reduction of Lactones and Lactams" @default.
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• W2055872765 doi "https://doi.org/10.1021/ja0351692" @default.
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