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- W2055880425 abstract "In vitro incubation of IgE-sensitized guinea-pig tracheal rings with 10––7M budesonide for 24 h significantly shifted the concentration-response curve to antigen by 5-fold to the right. Smooth muscle characteristics such as baseline tone, muscarinic contraction or relaxation to β2-receptor agonists and xanthines were not or only marginally affected by this exposure of airway tissue to a glucocorticoid drug. It is concluded that budesonide reduced anaphylactic IgE-driven release of contractile mediators." @default.
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- W2055880425 date "1989-01-01" @default.
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- W2055880425 title "Budesonide Reduces Sensitivity to Antigen but Does Not Alter Baseline Tone or Responsiveness to Carbachol, Terbutaline, and Enprofylline in IgE-Sensitized Guinea-Pig Tracheae" @default.
- W2055880425 doi "https://doi.org/10.1159/000234721" @default.
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