FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055898919> ?p ?o ?g. }

• W2055898919 endingPage "468" @default.
• W2055898919 startingPage "463" @default.
• W2055898919 abstract "It has been suggested that progesterone might affect bone metabolism. Dydrogesterone (DD) has a chemical structure very close to that of natural progesterone, without androgenic effects. We compared the effect of a daily treatment with DD and estradiol (E2, 40 μg/kg) on 70 female rats (8 weeks old), divided in seven groups: controls; ovariectomized (OVX); OVX + E2, OVX + DD 2.5 mg/kg; OVX + DD 5 mg/kg; OVX + E2 + DD 2.5 mg/kg; and OVX + E2 + DD 5 mg/kg. Two months later we studied estradiol, osteocalcin, and acid phosphatases (TRAP) levels; histomorphometric parameters at the trabecular part of the femur; and bone mineral density of the tibiae (trabecular and cortical areas) and caudal vertebrae (cortical bone) by dual energy X-ray absorptiometry (Hologic QDR 2000). In the OVX group, we found a nonsignificant increase of osteocalcin and TRAP, a decrease in the trabecular bone volume, and an increase in the intertrabecular distance. These variations were not seen in the groups treated with E2 (with or without DD). DD had no effect on trabecular architecture parameters. It induced a dose-dependent increase in the osteoclast number (TRAP + cells), without increase in trabecular separation. There was no difference in bone density of caudal vertebrae between the different groups, nor of the tibial density between the OVX and OVX + DD groups. The bone densities were not different in the control and E2-treated groups, with or without DD. During dydrogesterone treatment, there is an increase in osteoclast number, without an apparent increase in osteoclast function. Dydrogesterone did not prevent bone loss due to ovariectomy in rats, and it did not affect the protective effect of estradiol." @default.
• W2055898919 created "2016-06-24" @default.
• W2055898919 creator A5012384299 @default.
• W2055898919 creator A5048640756 @default.
• W2055898919 creator A5077099389 @default.
• W2055898919 creator A5078290825 @default.
• W2055898919 creator A5078876841 @default.
• W2055898919 creator A5089153314 @default.
• W2055898919 date "1996-11-01" @default.
• W2055898919 modified "2023-10-04" @default.
• W2055898919 title "Bone effects of dydrogesterone in ovariectomized rats: A biologic, histomorphometric, and densitometric study" @default.
• W2055898919 cites W1965568869 @default.
• W2055898919 cites W1970422815 @default.
• W2055898919 cites W1976106527 @default.
• W2055898919 cites W1977207568 @default.
• W2055898919 cites W1985132852 @default.
• W2055898919 cites W1985768095 @default.
• W2055898919 cites W1987354408 @default.
• W2055898919 cites W1990690071 @default.
• W2055898919 cites W1991003754 @default.
• W2055898919 cites W2002535656 @default.
• W2055898919 cites W2004477432 @default.
• W2055898919 cites W2008679227 @default.
• W2055898919 cites W2022145083 @default.
• W2055898919 cites W2027093084 @default.
• W2055898919 cites W2034461602 @default.
• W2055898919 cites W2038775630 @default.
• W2055898919 cites W2044010302 @default.
• W2055898919 cites W2069883047 @default.
• W2055898919 cites W2072427778 @default.
• W2055898919 cites W2087378917 @default.
• W2055898919 cites W2108759991 @default.
• W2055898919 cites W2135804654 @default.
• W2055898919 cites W2154697918 @default.
• W2055898919 cites W2167090221 @default.
• W2055898919 cites W2338124628 @default.
• W2055898919 cites W4243936541 @default.
• W2055898919 doi "https://doi.org/10.1016/s8756-3282(96)00244-x" @default.
• W2055898919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8922644" @default.
• W2055898919 hasPublicationYear "1996" @default.
• W2055898919 type Work @default.
• W2055898919 sameAs 2055898919 @default.
• W2055898919 citedByCount "10" @default.
• W2055898919 countsByYear W20558989192016 @default.
• W2055898919 crossrefType "journal-article" @default.
• W2055898919 hasAuthorship W2055898919A5012384299 @default.
• W2055898919 hasAuthorship W2055898919A5048640756 @default.
• W2055898919 hasAuthorship W2055898919A5077099389 @default.
• W2055898919 hasAuthorship W2055898919A5078290825 @default.
• W2055898919 hasAuthorship W2055898919A5078876841 @default.
• W2055898919 hasAuthorship W2055898919A5089153314 @default.
• W2055898919 hasBestOaLocation W20558989191 @default.
• W2055898919 hasConcept C105702510 @default.
• W2055898919 hasConcept C126322002 @default.
• W2055898919 hasConcept C131075544 @default.
• W2055898919 hasConcept C134018914 @default.
• W2055898919 hasConcept C160160445 @default.
• W2055898919 hasConcept C170033053 @default.
• W2055898919 hasConcept C170493617 @default.
• W2055898919 hasConcept C181199279 @default.
• W2055898919 hasConcept C185592680 @default.
• W2055898919 hasConcept C2776033226 @default.
• W2055898919 hasConcept C2776045411 @default.
• W2055898919 hasConcept C2776541429 @default.
• W2055898919 hasConcept C2776886416 @default.
• W2055898919 hasConcept C2777164284 @default.
• W2055898919 hasConcept C2779329777 @default.
• W2055898919 hasConcept C2781451080 @default.
• W2055898919 hasConcept C55493867 @default.
• W2055898919 hasConcept C673006 @default.
• W2055898919 hasConcept C71924100 @default.
• W2055898919 hasConcept C8264082 @default.
• W2055898919 hasConceptScore W2055898919C105702510 @default.
• W2055898919 hasConceptScore W2055898919C126322002 @default.
• W2055898919 hasConceptScore W2055898919C131075544 @default.
• W2055898919 hasConceptScore W2055898919C134018914 @default.
• W2055898919 hasConceptScore W2055898919C160160445 @default.
• W2055898919 hasConceptScore W2055898919C170033053 @default.
• W2055898919 hasConceptScore W2055898919C170493617 @default.
• W2055898919 hasConceptScore W2055898919C181199279 @default.
• W2055898919 hasConceptScore W2055898919C185592680 @default.
• W2055898919 hasConceptScore W2055898919C2776033226 @default.
• W2055898919 hasConceptScore W2055898919C2776045411 @default.
• W2055898919 hasConceptScore W2055898919C2776541429 @default.
• W2055898919 hasConceptScore W2055898919C2776886416 @default.
• W2055898919 hasConceptScore W2055898919C2777164284 @default.
• W2055898919 hasConceptScore W2055898919C2779329777 @default.
• W2055898919 hasConceptScore W2055898919C2781451080 @default.
• W2055898919 hasConceptScore W2055898919C55493867 @default.
• W2055898919 hasConceptScore W2055898919C673006 @default.
• W2055898919 hasConceptScore W2055898919C71924100 @default.
• W2055898919 hasConceptScore W2055898919C8264082 @default.
• W2055898919 hasIssue "5" @default.
• W2055898919 hasLocation W20558989191 @default.
• W2055898919 hasLocation W20558989192 @default.
• W2055898919 hasOpenAccess W2055898919 @default.
• W2055898919 hasPrimaryLocation W20558989191 @default.
• W2055898919 hasRelatedWork W1967422973 @default.

• next