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• W2055926511 abstract "We directly sequenced PCR fragments amplified from a porcine thyroid cDNA library with various synthetic primers based on the nucleotide sequence of bovine thyrotropin receptor (bTSHR) cDNA. A nucleotide sequence of 2410 bp was determined and its deduced amino acid sequence contained an open reading frame coding 764 amino acids, which showed 91.8% and 89.5% similarity to bTSHR and human TSH receptor, respectively. A hydrophobicity plot of the porcine protein suggested that it had a putative signal peptide and seven transmembrane domains. Chinese hamster ovary cells stably transfected with the cDNA could be specifically bound to bovine TSH (bTSH) and increased the intracellular cAMP level in response to bTSH and Graves' disease patients' sera stimulation." @default.
• W2055926511 created "2016-06-24" @default.
• W2055926511 creator A5046728598 @default.
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• W2055926511 date "2003-01-17" @default.
• W2055926511 modified "2023-09-25" @default.
• W2055926511 title "Molecular Cloning, Sequencing and Functional Expression of Porcine Thyrotropin (TSH) Receptor cDNA" @default.
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• W2055926511 doi "https://doi.org/10.1515/cclm.2003.121" @default.
• W2055926511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12880144" @default.
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