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- W2055929631 abstract "Ultra-short, high-field electric pulses permeabilize plasma and intracellular membranes. We report here nanosecond pulse-induced permeabilization of mitochondrial membranes in living cells. Using four independent methods based on fluorescent dyes--JC-1, rhodamine 123, tetramethyl rhodamine ethyl ester, and cobalt-quenched calcein--we show that as few as five, 4 ns, 10 MV/m pulses delivered at 1 kHz cause an increase of the inner mitochondrial membrane permeability and an associated loss of mitochondrial membrane potential. The most likely interpretation of these results is a pulse-induced permeabilization of the inner mitochondrial membrane." @default.
- W2055929631 created "2016-06-24" @default.
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- W2055929631 date "2011-08-01" @default.
- W2055929631 modified "2023-09-25" @default.
- W2055929631 title "Mitochondrial membrane permeabilization with nanosecond electric pulses" @default.
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- W2055929631 doi "https://doi.org/10.1109/iembs.2011.6090169" @default.
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