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• W2055975118 abstract "The sulfhydryl reagent thimerosal enhanced the sensitivity of hamster eggs to injected inositol 1,4,5‐trisphosphate (InsP 3 ) or Ca 2+ to generate regenerative Ca 2+ release from intracellular pools. A monoclonal antibody (mAb) to the InsP 3 receptor blocked both the InsP 3 ‐induced Ca 2+ release (IICR) and Ca 2+ ‐induced Ca 2+ release (CICR). The mAb also blocked Ca 2+ oscillations induced by thimerosal. The results indicate that thimerosal enhances IICR sensitized by cytosolic Ca 2+ , but not CICR from InsP 3 ‐insensitive pools, and causes repetitive Ca 2+ releases from InsP 3 ‐sensitive pools." @default.
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• W2055975118 date "1992-09-07" @default.
• W2055975118 modified "2023-10-15" @default.
• W2055975118 title "Antibody to the inositol trisphosphate receptor blocks thimerosalenhanced Ca²⁺‐induced Ca²⁺ release and Ca²⁺ oscillations in hamster eggs" @default.
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• W2055975118 doi "https://doi.org/10.1016/0014-5793(92)81090-9" @default.
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