Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055975119> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2055975119 abstract "The acute effects of diltiazem on coronary reactive hyperemia were studied in 12 patients with flow-limiting coronary stenosis. Reactive hyperemia was elicited by injection of 8 ml contrast medium into the left coronary artery, while coronary sinus blood flow and left ventricular and aortic pressures were continuously recorded. Relative magnitude of hyperemia was estimated by the ratio of coronary flow at peak hyperemia to baseline flow (hyperemic ratio). Coronary resistance was calculated as the ratio between mean aortic pressure minus left ventricular mean diastolic pressure and coronary sinus blood flow. The 12 patients studied had flow-limiting coronary stenosis since their hyperemic ratio was significantly restrained when compared to that of seven control subjects (1.45 +/- 0.17 vs 2.02 +/- 0.24, respectively; p less than 0.001). The intravenous infusion of diltiazem (0.30 mg X kg-1) reduced heart rate, mean aortic pressure, and myocardial oxygen consumption (all p less than 0.001). After diltiazem the hyperemic ratio was blunted when compared to the basal state (1.36 +/- 0.15 vs 1.45 +/- 0.17, respectively; p less than 0.05), and hyperemia volume was reduced (-33%; p less than 0.001). The decrease in coronary resistance at peak hyperemia was also reduced from -30 +/- 8% to -25 +/- 8% (p less than 0.05). We conclude that diltiazem blunts coronary reactive hyperemia in patients with demonstrated flow-limiting coronary stenosis. This reduction of coronary flow response to a hyperemic stimulus could favorably influence blood flow distribution in patients with significant coronary stenosis." @default.
- W2055975119 created "2016-06-24" @default.
- W2055975119 creator A5011583556 @default.
- W2055975119 creator A5021345205 @default.
- W2055975119 creator A5046672246 @default.
- W2055975119 creator A5063305601 @default.
- W2055975119 date "1986-12-01" @default.
- W2055975119 modified "2023-10-01" @default.
- W2055975119 title "Effect of diltiazem on coronary reactive hyperemia in patients with flow-limiting coronary artery stenosis" @default.
- W2055975119 cites W1968602190 @default.
- W2055975119 cites W1974983665 @default.
- W2055975119 cites W1976909816 @default.
- W2055975119 cites W1984682517 @default.
- W2055975119 cites W2003095803 @default.
- W2055975119 cites W2007660399 @default.
- W2055975119 cites W2013227026 @default.
- W2055975119 cites W2029769055 @default.
- W2055975119 cites W2031351701 @default.
- W2055975119 cites W2031534773 @default.
- W2055975119 cites W2035610186 @default.
- W2055975119 cites W2055044704 @default.
- W2055975119 cites W2055103382 @default.
- W2055975119 cites W2068373086 @default.
- W2055975119 cites W2070972264 @default.
- W2055975119 cites W2072346062 @default.
- W2055975119 cites W2076010459 @default.
- W2055975119 cites W2090028310 @default.
- W2055975119 cites W2091511539 @default.
- W2055975119 cites W2094103357 @default.
- W2055975119 cites W2094145779 @default.
- W2055975119 cites W2103341154 @default.
- W2055975119 cites W2109297399 @default.
- W2055975119 cites W2115207732 @default.
- W2055975119 cites W2121541273 @default.
- W2055975119 cites W2145164028 @default.
- W2055975119 cites W2150553724 @default.
- W2055975119 cites W2153035007 @default.
- W2055975119 cites W2337505739 @default.
- W2055975119 cites W2416915651 @default.
- W2055975119 cites W2419118980 @default.
- W2055975119 cites W2419491576 @default.
- W2055975119 cites W3140210769 @default.
- W2055975119 doi "https://doi.org/10.1016/0002-8703(86)90353-4" @default.
- W2055975119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3788770" @default.
- W2055975119 hasPublicationYear "1986" @default.
- W2055975119 type Work @default.
- W2055975119 sameAs 2055975119 @default.
- W2055975119 citedByCount "4" @default.
- W2055975119 crossrefType "journal-article" @default.
- W2055975119 hasAuthorship W2055975119A5011583556 @default.
- W2055975119 hasAuthorship W2055975119A5021345205 @default.
- W2055975119 hasAuthorship W2055975119A5046672246 @default.
- W2055975119 hasAuthorship W2055975119A5063305601 @default.
- W2055975119 hasConcept C126322002 @default.
- W2055975119 hasConcept C158846371 @default.
- W2055975119 hasConcept C164705383 @default.
- W2055975119 hasConcept C178853913 @default.
- W2055975119 hasConcept C2776157398 @default.
- W2055975119 hasConcept C2776741139 @default.
- W2055975119 hasConcept C2776820930 @default.
- W2055975119 hasConcept C2778259205 @default.
- W2055975119 hasConcept C2780007028 @default.
- W2055975119 hasConcept C3019128504 @default.
- W2055975119 hasConcept C39124391 @default.
- W2055975119 hasConcept C519063684 @default.
- W2055975119 hasConcept C71924100 @default.
- W2055975119 hasConceptScore W2055975119C126322002 @default.
- W2055975119 hasConceptScore W2055975119C158846371 @default.
- W2055975119 hasConceptScore W2055975119C164705383 @default.
- W2055975119 hasConceptScore W2055975119C178853913 @default.
- W2055975119 hasConceptScore W2055975119C2776157398 @default.
- W2055975119 hasConceptScore W2055975119C2776741139 @default.
- W2055975119 hasConceptScore W2055975119C2776820930 @default.
- W2055975119 hasConceptScore W2055975119C2778259205 @default.
- W2055975119 hasConceptScore W2055975119C2780007028 @default.
- W2055975119 hasConceptScore W2055975119C3019128504 @default.
- W2055975119 hasConceptScore W2055975119C39124391 @default.
- W2055975119 hasConceptScore W2055975119C519063684 @default.
- W2055975119 hasConceptScore W2055975119C71924100 @default.
- W2055975119 hasLocation W20559751191 @default.
- W2055975119 hasLocation W20559751192 @default.
- W2055975119 hasOpenAccess W2055975119 @default.
- W2055975119 hasPrimaryLocation W20559751191 @default.
- W2055975119 hasRelatedWork W1990153877 @default.
- W2055975119 hasRelatedWork W1999929948 @default.
- W2055975119 hasRelatedWork W2015365487 @default.
- W2055975119 hasRelatedWork W2048423547 @default.
- W2055975119 hasRelatedWork W2055975119 @default.
- W2055975119 hasRelatedWork W2090028310 @default.
- W2055975119 hasRelatedWork W2227573863 @default.
- W2055975119 hasRelatedWork W2401399753 @default.
- W2055975119 hasRelatedWork W2967765261 @default.
- W2055975119 hasRelatedWork W361976221 @default.
- W2055975119 isParatext "false" @default.
- W2055975119 isRetracted "false" @default.
- W2055975119 magId "2055975119" @default.
- W2055975119 workType "article" @default.