FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055984987> ?p ?o ?g. }

• W2055984987 endingPage "872" @default.
• W2055984987 startingPage "859" @default.
• W2055984987 abstract "Isolation rearing of rats produces a behavioral syndrome indicative of altered dopamine (DA) function in the nucleus accumbens (NAC). The present experiments extend these findings by investigating: (a) interactions between isolation rearing and repeated handling/testing on presynaptic DA function in the NAC using in vivo microdialysis; (b) the dose–response curve for the effects of d-amphetamine, and the responses elicited by high potassium, using in vivo microdialysis; and (c) postsynaptic function in isolates as indexed by DA receptor-linked cAMP production. Experiment 1 showed that both isolation rearing and repeated handling/testing had effects on monoamine function in the NAC. However, while both manipulations enhanced DA release evoked by d-amphetamine, only isolated rats had elevated basal DA levels. Opposite neurochemical changes were observed with respect to the serotonin metabolite 5-HIAA, isolates having lower, and repeatedly handled/tested animals having higher, extracellular levels. Experiment 2 provided evidence for enhanced d-amphetamine–evoked DA release in isolated animals, while potassium-evoked DA release was reduced. Experiment 3 provided evidence that the isolation rearing induced changes in presynaptic DA function were accompanied by postsynaptic changes. Specifically, the inhibitory influence of the D2 receptor on D1 receptor-stimulated cAMP production was attenuated in ventral striatal slices taken from isolates, suggesting a functional downregulation of D2 receptors." @default.
• W2055984987 created "2016-06-24" @default.
• W2055984987 creator A5013053391 @default.
• W2055984987 creator A5017054906 @default.
• W2055984987 creator A5020886846 @default.
• W2055984987 creator A5040950518 @default.
• W2055984987 creator A5045837411 @default.
• W2055984987 creator A5066735641 @default.
• W2055984987 creator A5087403435 @default.
• W2055984987 date "1998-04-01" @default.
• W2055984987 modified "2023-10-16" @default.
• W2055984987 title "Isolation Rearing in Rats: Pre- and Postsynaptic Changes in Striatal Dopaminergic Systems" @default.
• W2055984987 cites W1966242764 @default.
• W2055984987 cites W1972099271 @default.
• W2055984987 cites W1975740400 @default.
• W2055984987 cites W1985672723 @default.
• W2055984987 cites W1988580279 @default.
• W2055984987 cites W1989869372 @default.
• W2055984987 cites W1990888488 @default.
• W2055984987 cites W1994585641 @default.
• W2055984987 cites W2000222533 @default.
• W2055984987 cites W2017838119 @default.
• W2055984987 cites W2024186806 @default.
• W2055984987 cites W2026673385 @default.
• W2055984987 cites W2028495268 @default.
• W2055984987 cites W2029577632 @default.
• W2055984987 cites W2038004313 @default.
• W2055984987 cites W2040479766 @default.
• W2055984987 cites W2050017866 @default.
• W2055984987 cites W2050667075 @default.
• W2055984987 cites W2050783266 @default.
• W2055984987 cites W2052875410 @default.
• W2055984987 cites W2058202210 @default.
• W2055984987 cites W2061907117 @default.
• W2055984987 cites W2063198555 @default.
• W2055984987 cites W2066209808 @default.
• W2055984987 cites W2066571895 @default.
• W2055984987 cites W2068415834 @default.
• W2055984987 cites W2075950351 @default.
• W2055984987 cites W2084629876 @default.
• W2055984987 cites W2085631122 @default.
• W2055984987 cites W2086891644 @default.
• W2055984987 cites W2087452886 @default.
• W2055984987 cites W2087688448 @default.
• W2055984987 cites W2089199123 @default.
• W2055984987 cites W2103214756 @default.
• W2055984987 cites W2170769810 @default.
• W2055984987 cites W2497496491 @default.
• W2055984987 cites W4250520188 @default.
• W2055984987 doi "https://doi.org/10.1016/s0091-3057(97)00510-8" @default.
• W2055984987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9586842" @default.
• W2055984987 hasPublicationYear "1998" @default.
• W2055984987 type Work @default.
• W2055984987 sameAs 2055984987 @default.
• W2055984987 citedByCount "250" @default.
• W2055984987 countsByYear W20559849872012 @default.
• W2055984987 countsByYear W20559849872013 @default.
• W2055984987 countsByYear W20559849872014 @default.
• W2055984987 countsByYear W20559849872015 @default.
• W2055984987 countsByYear W20559849872016 @default.
• W2055984987 countsByYear W20559849872017 @default.
• W2055984987 countsByYear W20559849872018 @default.
• W2055984987 countsByYear W20559849872019 @default.
• W2055984987 countsByYear W20559849872020 @default.
• W2055984987 countsByYear W20559849872021 @default.
• W2055984987 countsByYear W20559849872022 @default.
• W2055984987 countsByYear W20559849872023 @default.
• W2055984987 crossrefType "journal-article" @default.
• W2055984987 hasAuthorship W2055984987A5013053391 @default.
• W2055984987 hasAuthorship W2055984987A5017054906 @default.
• W2055984987 hasAuthorship W2055984987A5020886846 @default.
• W2055984987 hasAuthorship W2055984987A5040950518 @default.
• W2055984987 hasAuthorship W2055984987A5045837411 @default.
• W2055984987 hasAuthorship W2055984987A5066735641 @default.
• W2055984987 hasAuthorship W2055984987A5087403435 @default.
• W2055984987 hasConcept C120069818 @default.
• W2055984987 hasConcept C126322002 @default.
• W2055984987 hasConcept C134018914 @default.
• W2055984987 hasConcept C137183658 @default.
• W2055984987 hasConcept C170493617 @default.
• W2055984987 hasConcept C187714386 @default.
• W2055984987 hasConcept C197341189 @default.
• W2055984987 hasConcept C25876315 @default.
• W2055984987 hasConcept C2775841634 @default.
• W2055984987 hasConcept C2775864247 @default.
• W2055984987 hasConcept C2775905480 @default.
• W2055984987 hasConcept C2776219046 @default.
• W2055984987 hasConcept C2776552330 @default.
• W2055984987 hasConcept C2777193897 @default.
• W2055984987 hasConcept C50156730 @default.
• W2055984987 hasConcept C513476851 @default.
• W2055984987 hasConcept C529278444 @default.
• W2055984987 hasConcept C71924100 @default.
• W2055984987 hasConcept C86803240 @default.
• W2055984987 hasConceptScore W2055984987C120069818 @default.
• W2055984987 hasConceptScore W2055984987C126322002 @default.
• W2055984987 hasConceptScore W2055984987C134018914 @default.
• W2055984987 hasConceptScore W2055984987C137183658 @default.

• next