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- W2056013963 endingPage "237" @default.
- W2056013963 startingPage "228" @default.
- W2056013963 abstract "Vascular calcification can occur in nearly all arterial beds and in both the medial and intimal layers. The initiating factors and clinical consequences depend on the underlying disease state and location of the calcification. The best studied manifestation is coronary artery calcification, in part because of the obvious clinical consequences, but also because of CT-based imaging modalities. In the general population, the presence of coronary artery calcification increases cardiovascular risk above that predicted by traditional Framingham risk factors, suggesting the presence of nontraditional risk factors. In patients with chronic kidney disease (CKD), coronary artery calcification is more prevalent and markedly more severe than in the general population. In these CKD patients, nontraditional risk factors such as oxidative stress, advanced glycation end products, and disordered mineral metabolism are also more prevalent and more severe and offer mechanistic insight into the pathogenesis of vascular calcification." @default.
- W2056013963 created "2016-06-24" @default.
- W2056013963 creator A5036155533 @default.
- W2056013963 creator A5074659892 @default.
- W2056013963 date "2012-04-03" @default.
- W2056013963 modified "2023-10-13" @default.
- W2056013963 title "Vascular Calcification: Pathophysiology and Risk Factors" @default.
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