Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056023611> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2056023611 endingPage "S68" @default.
- W2056023611 startingPage "S65" @default.
- W2056023611 abstract "The beneficial effect of yoghurt consumption on health and on the improvement of the mucosal immune system is well established, as is the diet-associated risk of colon cancer. In an experimental model in BALB/c mice we demonstrated that yoghurt added to the diet for 10 consecutive days, with the procedure repeated each 10 days for 6 months, inhibited the development of a colorectal carcinoma induced by 1,2 dimethylhydrazine (DMH). The immunoregulatory mechanisms involved in the inhibition of tumour growth by yoghurt were also examined in these studies. We determined B lymphocytes IgA(+) and IgG(+), as well as CD4(+) and CD8(+) T cells in the large intestine. We measured cellular apoptosis and the cytokines TNF-alpha, IFN-gamma and IL-10. An increase in the number of IgA(+) (P<0.01) was observed, but not in IgG(+) (P<0.01), or in the CD4(+) population (P<0.01) in the mice treated with DMH and yoghurt. While in the group with the carcinogen there was an enhancement in the IgG(+) B cells (P<0.01) and CD8(+) T cells (P<0.01). Yoghurt increased the number of apoptotic cells and induced IFN-gamma and TNF-alpha cytokine release, their production being regulated by an increase in IL-10 (P<0.001). We demonstrated that yoghurt may exert antitumour activity by a decrease in the inflammatory immune response mediated by IgA(+) increase, apoptosis induction and IL-10 release." @default.
- W2056023611 created "2016-06-24" @default.
- W2056023611 creator A5003955084 @default.
- W2056023611 creator A5014194724 @default.
- W2056023611 creator A5036002018 @default.
- W2056023611 creator A5045553607 @default.
- W2056023611 date "2002-07-30" @default.
- W2056023611 modified "2023-09-26" @default.
- W2056023611 title "Role of yoghurt in the prevention of colon cancer" @default.
- W2056023611 doi "https://doi.org/10.1038/sj.ejcn.1601490" @default.
- W2056023611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12142967" @default.
- W2056023611 hasPublicationYear "2002" @default.
- W2056023611 type Work @default.
- W2056023611 sameAs 2056023611 @default.
- W2056023611 citedByCount "97" @default.
- W2056023611 countsByYear W20560236112012 @default.
- W2056023611 countsByYear W20560236112013 @default.
- W2056023611 countsByYear W20560236112014 @default.
- W2056023611 countsByYear W20560236112015 @default.
- W2056023611 countsByYear W20560236112016 @default.
- W2056023611 countsByYear W20560236112017 @default.
- W2056023611 countsByYear W20560236112018 @default.
- W2056023611 countsByYear W20560236112019 @default.
- W2056023611 countsByYear W20560236112020 @default.
- W2056023611 countsByYear W20560236112021 @default.
- W2056023611 countsByYear W20560236112022 @default.
- W2056023611 countsByYear W20560236112023 @default.
- W2056023611 crossrefType "journal-article" @default.
- W2056023611 hasAuthorship W2056023611A5003955084 @default.
- W2056023611 hasAuthorship W2056023611A5014194724 @default.
- W2056023611 hasAuthorship W2056023611A5036002018 @default.
- W2056023611 hasAuthorship W2056023611A5045553607 @default.
- W2056023611 hasBestOaLocation W20560236111 @default.
- W2056023611 hasConcept C114246631 @default.
- W2056023611 hasConcept C121608353 @default.
- W2056023611 hasConcept C126322002 @default.
- W2056023611 hasConcept C167672396 @default.
- W2056023611 hasConcept C17991360 @default.
- W2056023611 hasConcept C190283241 @default.
- W2056023611 hasConcept C203014093 @default.
- W2056023611 hasConcept C2778452354 @default.
- W2056023611 hasConcept C2778690821 @default.
- W2056023611 hasConcept C2779932572 @default.
- W2056023611 hasConcept C2908647359 @default.
- W2056023611 hasConcept C2991914351 @default.
- W2056023611 hasConcept C526805850 @default.
- W2056023611 hasConcept C55493867 @default.
- W2056023611 hasConcept C71924100 @default.
- W2056023611 hasConcept C86803240 @default.
- W2056023611 hasConcept C8891405 @default.
- W2056023611 hasConcept C99454951 @default.
- W2056023611 hasConceptScore W2056023611C114246631 @default.
- W2056023611 hasConceptScore W2056023611C121608353 @default.
- W2056023611 hasConceptScore W2056023611C126322002 @default.
- W2056023611 hasConceptScore W2056023611C167672396 @default.
- W2056023611 hasConceptScore W2056023611C17991360 @default.
- W2056023611 hasConceptScore W2056023611C190283241 @default.
- W2056023611 hasConceptScore W2056023611C203014093 @default.
- W2056023611 hasConceptScore W2056023611C2778452354 @default.
- W2056023611 hasConceptScore W2056023611C2778690821 @default.
- W2056023611 hasConceptScore W2056023611C2779932572 @default.
- W2056023611 hasConceptScore W2056023611C2908647359 @default.
- W2056023611 hasConceptScore W2056023611C2991914351 @default.
- W2056023611 hasConceptScore W2056023611C526805850 @default.
- W2056023611 hasConceptScore W2056023611C55493867 @default.
- W2056023611 hasConceptScore W2056023611C71924100 @default.
- W2056023611 hasConceptScore W2056023611C86803240 @default.
- W2056023611 hasConceptScore W2056023611C8891405 @default.
- W2056023611 hasConceptScore W2056023611C99454951 @default.
- W2056023611 hasIssue "S3" @default.
- W2056023611 hasLocation W20560236111 @default.
- W2056023611 hasLocation W20560236112 @default.
- W2056023611 hasOpenAccess W2056023611 @default.
- W2056023611 hasPrimaryLocation W20560236111 @default.
- W2056023611 hasRelatedWork W181678093 @default.
- W2056023611 hasRelatedWork W1985827206 @default.
- W2056023611 hasRelatedWork W1993985418 @default.
- W2056023611 hasRelatedWork W2043331267 @default.
- W2056023611 hasRelatedWork W2047209980 @default.
- W2056023611 hasRelatedWork W2188923115 @default.
- W2056023611 hasRelatedWork W2962756305 @default.
- W2056023611 hasRelatedWork W3017248443 @default.
- W2056023611 hasRelatedWork W2185732136 @default.
- W2056023611 hasRelatedWork W2396811992 @default.
- W2056023611 hasVolume "56" @default.
- W2056023611 isParatext "false" @default.
- W2056023611 isRetracted "false" @default.
- W2056023611 magId "2056023611" @default.
- W2056023611 workType "article" @default.