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- W2056055556 abstract "A conventional synthesis of α-thioglycoside of sialic acid as a glycomonomer was accomplished. Radical copolymerization of the glycomonomer with vinyl acetate proceeded smoothly to afford a new class of glycopolymers having thiosialoside residues, in which all protection was removed by a combination of transesterification and saponification to provide a water-soluble thiosialoside cluster. The results of a preliminary study on biological responses against influenza virus neuraminidases using the thiosialoside polymer as a candidate for a neuraminidase inhibitor showed that the glycopolymer has potent inhibitory activity against the neuraminidases." @default.
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- W2056055556 date "2007-07-01" @default.
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- W2056055556 title "Novel linear polymers bearing thiosialosides as pendant-type epitopes for influenza neuraminidase inhibitors" @default.
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- W2056055556 doi "https://doi.org/10.1016/j.bmcl.2007.05.016" @default.
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