FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056103673> ?p ?o ?g. }

• W2056103673 endingPage "1198" @default.
• W2056103673 startingPage "1194" @default.
• W2056103673 abstract "Oral cancer is a common and lethal malignancy. Direct contact between saliva and the oral cancer lesion makes measurement of tumour markers in saliva an attractive alternative to serum testing.We tested 19 tongue cancer patients, measuring the levels of 8 salivary markers related to oxidative stress, DNA repair, carcinogenesis, metastasis and cellular proliferation and death.Five markers increased in cancer patients by 39-246%: carbonyls, lactate dehydrogenase, metalloproteinase-9 (MMP-9), Ki67 and Cyclin D1 (CycD1) (P< or =0.01). Three markers decreased by 16-29%: 8-oxoguanine DNA glycosylase, phosphorylated-Src and mammary serine protease inhibitor (Maspin) (P< or =0.01). Increase in salivary carbonyls was profound (by 246%, P=0.012); alterations in CycD1 (87% increase, P=0.000006) and Maspin (29% decrease, P=0.007) were especially significant. Sensitivity values of these eight analysed markers ranged from 58% to 100%; specificity values ranged from 42% to 100%. Both values were especially high for the CycD1 and Maspin markers, 100% for each value of each marker. These were also high for carbonyls, 90% and 80%, respectively, and for MMP-9, 100% and 79%, respectively.The significance of each salivary alteration is discussed. As all alterations correlated with each other, they may belong to a single carcinogenetic network. Cancer-related changes in salivary tumour markers may be used as a diagnostic tool for diagnosis, prognosis and post-operative monitoring." @default.
• W2056103673 created "2016-06-24" @default.
• W2056103673 creator A5000406713 @default.
• W2056103673 creator A5025053584 @default.
• W2056103673 creator A5048504899 @default.
• W2056103673 creator A5050201213 @default.
• W2056103673 creator A5061834107 @default.
• W2056103673 creator A5066078143 @default.
• W2056103673 creator A5072052224 @default.
• W2056103673 creator A5076157604 @default.
• W2056103673 date "2009-09-29" @default.
• W2056103673 modified "2023-10-18" @default.
• W2056103673 title "Salivary analysis of oral cancer biomarkers" @default.
• W2056103673 cites W1501512050 @default.
• W2056103673 cites W1558762677 @default.
• W2056103673 cites W1660103710 @default.
• W2056103673 cites W1965684055 @default.
• W2056103673 cites W1987029158 @default.
• W2056103673 cites W1988034564 @default.
• W2056103673 cites W1989790551 @default.
• W2056103673 cites W1991119498 @default.
• W2056103673 cites W1994924724 @default.
• W2056103673 cites W1996242455 @default.
• W2056103673 cites W1996933787 @default.
• W2056103673 cites W2014358017 @default.
• W2056103673 cites W2019827151 @default.
• W2056103673 cites W2020813499 @default.
• W2056103673 cites W2022685589 @default.
• W2056103673 cites W2023418017 @default.
• W2056103673 cites W2032863971 @default.
• W2056103673 cites W2035550311 @default.
• W2056103673 cites W2037633031 @default.
• W2056103673 cites W2043167035 @default.
• W2056103673 cites W2063801914 @default.
• W2056103673 cites W2075082193 @default.
• W2056103673 cites W2083192586 @default.
• W2056103673 cites W2096370389 @default.
• W2056103673 cites W2103469703 @default.
• W2056103673 cites W2117204437 @default.
• W2056103673 cites W2118107583 @default.
• W2056103673 cites W2137034692 @default.
• W2056103673 cites W2143752038 @default.
• W2056103673 cites W2151224963 @default.
• W2056103673 doi "https://doi.org/10.1038/sj.bjc.6605290" @default.
• W2056103673 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2768098" @default.
• W2056103673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19789535" @default.
• W2056103673 hasPublicationYear "2009" @default.
• W2056103673 type Work @default.
• W2056103673 sameAs 2056103673 @default.
• W2056103673 citedByCount "141" @default.
• W2056103673 countsByYear W20561036732012 @default.
• W2056103673 countsByYear W20561036732013 @default.
• W2056103673 countsByYear W20561036732014 @default.
• W2056103673 countsByYear W20561036732015 @default.
• W2056103673 countsByYear W20561036732016 @default.
• W2056103673 countsByYear W20561036732017 @default.
• W2056103673 countsByYear W20561036732018 @default.
• W2056103673 countsByYear W20561036732019 @default.
• W2056103673 countsByYear W20561036732020 @default.
• W2056103673 countsByYear W20561036732021 @default.
• W2056103673 countsByYear W20561036732022 @default.
• W2056103673 countsByYear W20561036732023 @default.
• W2056103673 crossrefType "journal-article" @default.
• W2056103673 hasAuthorship W2056103673A5000406713 @default.
• W2056103673 hasAuthorship W2056103673A5025053584 @default.
• W2056103673 hasAuthorship W2056103673A5048504899 @default.
• W2056103673 hasAuthorship W2056103673A5050201213 @default.
• W2056103673 hasAuthorship W2056103673A5061834107 @default.
• W2056103673 hasAuthorship W2056103673A5066078143 @default.
• W2056103673 hasAuthorship W2056103673A5072052224 @default.
• W2056103673 hasAuthorship W2056103673A5076157604 @default.
• W2056103673 hasBestOaLocation W20561036731 @default.
• W2056103673 hasConcept C121608353 @default.
• W2056103673 hasConcept C126322002 @default.
• W2056103673 hasConcept C142724271 @default.
• W2056103673 hasConcept C143998085 @default.
• W2056103673 hasConcept C2778900538 @default.
• W2056103673 hasConcept C2779013556 @default.
• W2056103673 hasConcept C2779399171 @default.
• W2056103673 hasConcept C502942594 @default.
• W2056103673 hasConcept C504460877 @default.
• W2056103673 hasConcept C555283112 @default.
• W2056103673 hasConcept C71924100 @default.
• W2056103673 hasConcept C86803240 @default.
• W2056103673 hasConcept C90924648 @default.
• W2056103673 hasConceptScore W2056103673C121608353 @default.
• W2056103673 hasConceptScore W2056103673C126322002 @default.
• W2056103673 hasConceptScore W2056103673C142724271 @default.
• W2056103673 hasConceptScore W2056103673C143998085 @default.
• W2056103673 hasConceptScore W2056103673C2778900538 @default.
• W2056103673 hasConceptScore W2056103673C2779013556 @default.
• W2056103673 hasConceptScore W2056103673C2779399171 @default.
• W2056103673 hasConceptScore W2056103673C502942594 @default.
• W2056103673 hasConceptScore W2056103673C504460877 @default.
• W2056103673 hasConceptScore W2056103673C555283112 @default.
• W2056103673 hasConceptScore W2056103673C71924100 @default.
• W2056103673 hasConceptScore W2056103673C86803240 @default.
• W2056103673 hasConceptScore W2056103673C90924648 @default.

• next