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- W2056123060 abstract "Functionalization of single-walled carbon nanotubes (SWCNTs) with nitrile groups, followed by further reactions allowed direct attachment of azithromycin and its N-demethyl derivative to the side-walls of SWCNTs for the first time. With these approaches, the cleavable ester or thioamide bonds are formed to connect azithromycin to SWCNTs resulting in azithromycin-SWCNT conjugates. These cleavable bonds are able to control molecular release from nanotube surfaces which are generally applicable to a variety of hybrid materials based on SWCNTs. A non-covalent azithromycin-SWCNT has also been compared with azithromycin-SWCNTs conjugates. Thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR), UV–vis, and Raman spectroscopies give hints on the characterization of azithromycin-SWCNT. Both drug release and antimicrobial activity of azithromycin-SWCNT conjugates were also tested." @default.
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- W2056123060 date "2014-01-01" @default.
- W2056123060 modified "2023-09-25" @default.
- W2056123060 title "Characterization of ester- or thioamide-functionalized single-walled carbon nanotube-azithromycin conjugates" @default.
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- W2056123060 doi "https://doi.org/10.1016/j.apsusc.2013.09.159" @default.
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