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- W2056142175 abstract "Crotamiton, which is a mixture of cis and trans isomers, was investigated by several separation techniques. One of the HPLC modes, in which crotamiton eluted as a single peak, was selected for the determination of five active ingredients (crotamiton, prednisolone, glycyrrhetinic acid, dibucaine and chlorhexidine hydrochloride) in an ointment. The simultaneous determination was performed using isocratic reversed-phase mode within 20 min by employing an octyl (C8) column and a mobile phase containing sodium dodecyl sulfate (SDS) and 2-propanol. The method was successfully applied to quality control and stability testing of the ointment." @default.
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- W2056142175 date "1997-06-01" @default.
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- W2056142175 title "Chromatography of crotamiton and its application to the determination of active ingredients in ointments" @default.
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- W2056142175 doi "https://doi.org/10.1016/s0731-7085(96)02052-3" @default.
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