Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056142961> ?p ?o ?g. }
- W2056142961 endingPage "284" @default.
- W2056142961 startingPage "278" @default.
- W2056142961 abstract "PAX3 is a transcription factor important for neural, muscle, and facial development in vertebrates. To identify genes regulated by PAX3, we used a cyclic amplification and selection of targets (CASTing) strategy to isolate cis-regulatory elements bound by PAX3. CASTing libraries were constructed with mouse DNA fragments bound by mouse PAX3, and human genomic DNA fragments bound by human PAX3 and the fusion protein PAX3-FKHR. Approximately 1000 clones were sequenced from each of these three libraries. Numerous putative targets of PAX3 and PAX3-FKHR were identified and six genes, Itm2A, Fath, FLT1, TGFA, BVES, and EN2, were examined closely. The genomic DNA fragments near these genes contain PAX3 binding sites and confer PAX3-dependent regulation. The expression levels of these genes correlate with the PAX3 expression levels in mouse embryos or with PAX3-FKHR expression levels in rhabdomyosarcoma cell lines, and indicate they may be part of the PAX3 regulatory circuitry during embryogenesis and tumor formation." @default.
- W2056142961 created "2016-06-24" @default.
- W2056142961 creator A5003408751 @default.
- W2056142961 creator A5013409747 @default.
- W2056142961 creator A5016323563 @default.
- W2056142961 creator A5017228589 @default.
- W2056142961 creator A5025441472 @default.
- W2056142961 creator A5042165276 @default.
- W2056142961 date "2002-03-01" @default.
- W2056142961 modified "2023-10-12" @default.
- W2056142961 title "Identification of Target Genes Regulated by PAX3 and PAX3–FKHR in Embryogenesis and Alveolar Rhabdomyosarcoma" @default.
- W2056142961 cites W1785629757 @default.
- W2056142961 cites W1790840575 @default.
- W2056142961 cites W1951685919 @default.
- W2056142961 cites W1965724931 @default.
- W2056142961 cites W1967978971 @default.
- W2056142961 cites W1968235561 @default.
- W2056142961 cites W1977520190 @default.
- W2056142961 cites W1986400206 @default.
- W2056142961 cites W1997408529 @default.
- W2056142961 cites W1998329643 @default.
- W2056142961 cites W1999638259 @default.
- W2056142961 cites W2000146676 @default.
- W2056142961 cites W2001664444 @default.
- W2056142961 cites W2004266019 @default.
- W2056142961 cites W2007087864 @default.
- W2056142961 cites W2017650796 @default.
- W2056142961 cites W2020257254 @default.
- W2056142961 cites W2032482825 @default.
- W2056142961 cites W2033927106 @default.
- W2056142961 cites W2033971631 @default.
- W2056142961 cites W2034793893 @default.
- W2056142961 cites W2037100222 @default.
- W2056142961 cites W2037447292 @default.
- W2056142961 cites W2040092510 @default.
- W2056142961 cites W2042658814 @default.
- W2056142961 cites W2044825415 @default.
- W2056142961 cites W2044837031 @default.
- W2056142961 cites W2047469022 @default.
- W2056142961 cites W2048268714 @default.
- W2056142961 cites W2052207224 @default.
- W2056142961 cites W2055109383 @default.
- W2056142961 cites W2062853980 @default.
- W2056142961 cites W2074222004 @default.
- W2056142961 cites W2082900218 @default.
- W2056142961 cites W2088043742 @default.
- W2056142961 cites W2091166404 @default.
- W2056142961 cites W2092119165 @default.
- W2056142961 cites W2109555585 @default.
- W2056142961 cites W2119521084 @default.
- W2056142961 cites W2120690461 @default.
- W2056142961 cites W2124636729 @default.
- W2056142961 cites W2126732550 @default.
- W2056142961 cites W2139463895 @default.
- W2056142961 cites W2141046053 @default.
- W2056142961 cites W2142784023 @default.
- W2056142961 cites W2161178884 @default.
- W2056142961 cites W2186534860 @default.
- W2056142961 cites W2626390606 @default.
- W2056142961 cites W4246639364 @default.
- W2056142961 doi "https://doi.org/10.1006/geno.2002.6703" @default.
- W2056142961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11863357" @default.
- W2056142961 hasPublicationYear "2002" @default.
- W2056142961 type Work @default.
- W2056142961 sameAs 2056142961 @default.
- W2056142961 citedByCount "63" @default.
- W2056142961 countsByYear W20561429612012 @default.
- W2056142961 countsByYear W20561429612013 @default.
- W2056142961 countsByYear W20561429612014 @default.
- W2056142961 countsByYear W20561429612015 @default.
- W2056142961 countsByYear W20561429612016 @default.
- W2056142961 countsByYear W20561429612017 @default.
- W2056142961 countsByYear W20561429612018 @default.
- W2056142961 countsByYear W20561429612020 @default.
- W2056142961 countsByYear W20561429612021 @default.
- W2056142961 countsByYear W20561429612023 @default.
- W2056142961 crossrefType "journal-article" @default.
- W2056142961 hasAuthorship W2056142961A5003408751 @default.
- W2056142961 hasAuthorship W2056142961A5013409747 @default.
- W2056142961 hasAuthorship W2056142961A5016323563 @default.
- W2056142961 hasAuthorship W2056142961A5017228589 @default.
- W2056142961 hasAuthorship W2056142961A5025441472 @default.
- W2056142961 hasAuthorship W2056142961A5042165276 @default.
- W2056142961 hasConcept C104317684 @default.
- W2056142961 hasConcept C123894998 @default.
- W2056142961 hasConcept C142724271 @default.
- W2056142961 hasConcept C168609215 @default.
- W2056142961 hasConcept C2776522094 @default.
- W2056142961 hasConcept C2778256501 @default.
- W2056142961 hasConcept C2780844630 @default.
- W2056142961 hasConcept C40767141 @default.
- W2056142961 hasConcept C54355233 @default.
- W2056142961 hasConcept C71924100 @default.
- W2056142961 hasConcept C86339819 @default.
- W2056142961 hasConcept C86803240 @default.
- W2056142961 hasConceptScore W2056142961C104317684 @default.
- W2056142961 hasConceptScore W2056142961C123894998 @default.
- W2056142961 hasConceptScore W2056142961C142724271 @default.