FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056152001> ?p ?o ?g. }

• W2056152001 endingPage "281" @default.
• W2056152001 startingPage "271" @default.
• W2056152001 abstract "Transport of antiretroviral agents across the blood-brain barrier (BBB) is of key importance to the treatment for the acquired immunodeficiency syndrome (AIDS). In this study, impact of exposure to electromagnetic field (EMF) on the permeability of saquinavir (SQV) across BBB was investigated. The in vitro BBB model was based on human brain-microvascular endothelial cells (HBMEC), and the concentration of SQV in receiver chamber of the transport system was evaluated. Polybutylcyanoacrylate (PBCA), methylmethacrylate-sulfopropylmethacrylate (MMA-SPM), and solid lipid nanoparticle (SLN) were employed as carriers for the delivery systems. Cytotoxicity of SLN decreased as content of cacao butter increased. Power of 5mV was apposite for the study on HBMEC without obvious apoptosis. Square wave produced greater permeability than sine and triangle waves. The carrier order on permeability of SQV across HBMEC monolayer under exposure to EMF was SLN>PBCA>MMA-SPM. Also, a larger frequency, modulation or depth of amplitude modulation (AM), or modulation or deviation of frequency modulation (FM) yielded a greater permeability. Besides, enhancement of permeability by AM wave was more significant than that by FM wave. Transport behavior of SQV across BBB was strongly influenced by the combination of nanoparticulate PBCA, MMA-SPM, and SLN with EMF exposure. This combination would be beneficial to the clinical application to the therapy of AIDS and other brain-related diseases." @default.
• W2056152001 created "2016-06-24" @default.
• W2056152001 creator A5063177635 @default.
• W2056152001 creator A5075889581 @default.
• W2056152001 date "2008-03-03" @default.
• W2056152001 modified "2023-09-26" @default.
• W2056152001 title "Electromagnetic interference in the permeability of saquinavir across the blood–brain barrier using nanoparticulate carriers" @default.
• W2056152001 cites W1967221196 @default.
• W2056152001 cites W1989415566 @default.
• W2056152001 cites W1993636611 @default.
• W2056152001 cites W1997128098 @default.
• W2056152001 cites W2000269813 @default.
• W2056152001 cites W2003389748 @default.
• W2056152001 cites W2009424304 @default.
• W2056152001 cites W2020882358 @default.
• W2056152001 cites W2022981781 @default.
• W2056152001 cites W2024773352 @default.
• W2056152001 cites W2032959148 @default.
• W2056152001 cites W2044780826 @default.
• W2056152001 cites W2046965609 @default.
• W2056152001 cites W2050795398 @default.
• W2056152001 cites W2052055355 @default.
• W2056152001 cites W2057520272 @default.
• W2056152001 cites W2060909088 @default.
• W2056152001 cites W2064685157 @default.
• W2056152001 cites W2067399621 @default.
• W2056152001 cites W2076615333 @default.
• W2056152001 cites W2092370160 @default.
• W2056152001 cites W2094595473 @default.
• W2056152001 cites W2102738613 @default.
• W2056152001 cites W2118662008 @default.
• W2056152001 cites W2119557341 @default.
• W2056152001 cites W2122032638 @default.
• W2056152001 cites W2134344823 @default.
• W2056152001 cites W2135759852 @default.
• W2056152001 cites W2140453379 @default.
• W2056152001 cites W2163695841 @default.
• W2056152001 cites W2168844674 @default.
• W2056152001 cites W2260778754 @default.
• W2056152001 cites W62613713 @default.
• W2056152001 doi "https://doi.org/10.1016/j.ijpharm.2007.09.020" @default.
• W2056152001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17976933" @default.
• W2056152001 hasPublicationYear "2008" @default.
• W2056152001 type Work @default.
• W2056152001 sameAs 2056152001 @default.
• W2056152001 citedByCount "80" @default.
• W2056152001 countsByYear W20561520012012 @default.
• W2056152001 countsByYear W20561520012013 @default.
• W2056152001 countsByYear W20561520012014 @default.
• W2056152001 countsByYear W20561520012015 @default.
• W2056152001 countsByYear W20561520012016 @default.
• W2056152001 countsByYear W20561520012017 @default.
• W2056152001 countsByYear W20561520012018 @default.
• W2056152001 countsByYear W20561520012019 @default.
• W2056152001 countsByYear W20561520012020 @default.
• W2056152001 countsByYear W20561520012021 @default.
• W2056152001 countsByYear W20561520012023 @default.
• W2056152001 crossrefType "journal-article" @default.
• W2056152001 hasAuthorship W2056152001A5063177635 @default.
• W2056152001 hasAuthorship W2056152001A5075889581 @default.
• W2056152001 hasConcept C109316439 @default.
• W2056152001 hasConcept C120882062 @default.
• W2056152001 hasConcept C12554922 @default.
• W2056152001 hasConcept C126322002 @default.
• W2056152001 hasConcept C13245373 @default.
• W2056152001 hasConcept C142462285 @default.
• W2056152001 hasConcept C185592680 @default.
• W2056152001 hasConcept C202751555 @default.
• W2056152001 hasConcept C203014093 @default.
• W2056152001 hasConcept C2776937687 @default.
• W2056152001 hasConcept C2778402981 @default.
• W2056152001 hasConcept C2780035454 @default.
• W2056152001 hasConcept C2993143319 @default.
• W2056152001 hasConcept C3013748606 @default.
• W2056152001 hasConcept C41625074 @default.
• W2056152001 hasConcept C529278444 @default.
• W2056152001 hasConcept C55493867 @default.
• W2056152001 hasConcept C71924100 @default.
• W2056152001 hasConcept C86803240 @default.
• W2056152001 hasConcept C98274493 @default.
• W2056152001 hasConceptScore W2056152001C109316439 @default.
• W2056152001 hasConceptScore W2056152001C120882062 @default.
• W2056152001 hasConceptScore W2056152001C12554922 @default.
• W2056152001 hasConceptScore W2056152001C126322002 @default.
• W2056152001 hasConceptScore W2056152001C13245373 @default.
• W2056152001 hasConceptScore W2056152001C142462285 @default.
• W2056152001 hasConceptScore W2056152001C185592680 @default.
• W2056152001 hasConceptScore W2056152001C202751555 @default.
• W2056152001 hasConceptScore W2056152001C203014093 @default.
• W2056152001 hasConceptScore W2056152001C2776937687 @default.
• W2056152001 hasConceptScore W2056152001C2778402981 @default.
• W2056152001 hasConceptScore W2056152001C2780035454 @default.
• W2056152001 hasConceptScore W2056152001C2993143319 @default.
• W2056152001 hasConceptScore W2056152001C3013748606 @default.
• W2056152001 hasConceptScore W2056152001C41625074 @default.
• W2056152001 hasConceptScore W2056152001C529278444 @default.
• W2056152001 hasConceptScore W2056152001C55493867 @default.
• W2056152001 hasConceptScore W2056152001C71924100 @default.

• next