FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056160771> ?p ?o ?g. }

• W2056160771 endingPage "e007049" @default.
• W2056160771 startingPage "e007049" @default.
• W2056160771 abstract "<h3>Objectives</h3> The prognostic utility of serum C reactive protein (CRP) alone in sepsis is controversial. We used decision curve analysis (DCA) to evaluate the clinical usefulness of combining serum CRP levels with the CUBR-65 score in patients with suspected sepsis. <h3>Design</h3> Retrospective cohort study. <h3>Setting</h3> Emergency department (ED) of an urban teaching hospital in Japan. <h3>Participants</h3> Consecutive ED patients over 15 years of age who were admitted to the hospital after having a blood culture taken in the ED between 1 January 2010 and 31 December 2012. <h3>Main outcome measures</h3> 30-day in-hospital mortality. <h3>Results</h3> Data from 1262 patients were analysed for score evaluation. The 30-day in-hospital mortality was 8.4%. Multivariable analysis showed that serum CRP ≥150 mg/L was an independent predictor of death (adjusted OR 2.0; 95% CI 1.3 to 3.1). We compared the predictive performance of CURB-65 with the performance of a modified CURB-65 with that included CRP (≥150 mg/L) to quantify the clinical usefulness of combining serum CRP with CURB-65. The areas under the receiver operating characteristics curves of CURB-65 and a modified CURB-65 were 0.76 (95% CI 0.72 to 0.80) and 0.77 (95% CI 0.72 to 0.81), respectively. Both models had good calibration for mortality and were useful among threshold probabilities from 0% to 30%. However, while incorporating CRP into CURB-65 yielded a significant category-free net reclassification improvement of 0.387 (95% CI 0.193 to 0.582) and integrated discrimination improvement of 0.015 (95% CI 0.004 to 0.027), DCA showed that CURB-65 and the modified CURB-65 score had comparable net benefits for prediction of mortality. <h3>Conclusions</h3> Measurement of serum CRP added limited clinical usefulness to CURB-65 in predicting mortality in patients with clinically suspected sepsis, regardless of the source." @default.
• W2056160771 created "2016-06-24" @default.
• W2056160771 creator A5018869061 @default.
• W2056160771 creator A5022751311 @default.
• W2056160771 creator A5028341023 @default.
• W2056160771 creator A5029051349 @default.
• W2056160771 creator A5032930081 @default.
• W2056160771 creator A5037141327 @default.
• W2056160771 creator A5057534039 @default.
• W2056160771 creator A5084729535 @default.
• W2056160771 creator A5089998559 @default.
• W2056160771 creator A5091454801 @default.
• W2056160771 date "2015-04-28" @default.
• W2056160771 modified "2023-09-27" @default.
• W2056160771 title "Prognostic utility of serum CRP levels in combination with CURB-65 in patients with clinically suspected sepsis: a decision curve analysis" @default.
• W2056160771 cites W1998286193 @default.
• W2056160771 cites W1998788099 @default.
• W2056160771 cites W2008513614 @default.
• W2056160771 cites W2015329932 @default.
• W2056160771 cites W2018195004 @default.
• W2056160771 cites W2023732110 @default.
• W2056160771 cites W2024887237 @default.
• W2056160771 cites W2026901643 @default.
• W2056160771 cites W2037668591 @default.
• W2056160771 cites W2039721590 @default.
• W2056160771 cites W2042080283 @default.
• W2056160771 cites W2045030989 @default.
• W2056160771 cites W2045308848 @default.
• W2056160771 cites W2049770538 @default.
• W2056160771 cites W2053583905 @default.
• W2056160771 cites W2067989944 @default.
• W2056160771 cites W2068583723 @default.
• W2056160771 cites W2081752470 @default.
• W2056160771 cites W2084033659 @default.
• W2056160771 cites W2087653414 @default.
• W2056160771 cites W2102361557 @default.
• W2056160771 cites W2103314341 @default.
• W2056160771 cites W2103645914 @default.
• W2056160771 cites W2119910794 @default.
• W2056160771 cites W2121689436 @default.
• W2056160771 cites W2123039957 @default.
• W2056160771 cites W2127653619 @default.
• W2056160771 cites W2132519658 @default.
• W2056160771 cites W2138904389 @default.
• W2056160771 cites W2140074098 @default.
• W2056160771 cites W2157150997 @default.
• W2056160771 cites W2166339706 @default.
• W2056160771 cites W2166607382 @default.
• W2056160771 cites W2170285826 @default.
• W2056160771 cites W4233921710 @default.
• W2056160771 cites W4243715800 @default.
• W2056160771 doi "https://doi.org/10.1136/bmjopen-2014-007049" @default.
• W2056160771 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4420934" @default.
• W2056160771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25922102" @default.
• W2056160771 hasPublicationYear "2015" @default.
• W2056160771 type Work @default.
• W2056160771 sameAs 2056160771 @default.
• W2056160771 citedByCount "18" @default.
• W2056160771 countsByYear W20561607712016 @default.
• W2056160771 countsByYear W20561607712018 @default.
• W2056160771 countsByYear W20561607712019 @default.
• W2056160771 countsByYear W20561607712020 @default.
• W2056160771 countsByYear W20561607712021 @default.
• W2056160771 countsByYear W20561607712022 @default.
• W2056160771 countsByYear W20561607712023 @default.
• W2056160771 crossrefType "journal-article" @default.
• W2056160771 hasAuthorship W2056160771A5018869061 @default.
• W2056160771 hasAuthorship W2056160771A5022751311 @default.
• W2056160771 hasAuthorship W2056160771A5028341023 @default.
• W2056160771 hasAuthorship W2056160771A5029051349 @default.
• W2056160771 hasAuthorship W2056160771A5032930081 @default.
• W2056160771 hasAuthorship W2056160771A5037141327 @default.
• W2056160771 hasAuthorship W2056160771A5057534039 @default.
• W2056160771 hasAuthorship W2056160771A5084729535 @default.
• W2056160771 hasAuthorship W2056160771A5089998559 @default.
• W2056160771 hasAuthorship W2056160771A5091454801 @default.
• W2056160771 hasBestOaLocation W20561607711 @default.
• W2056160771 hasConcept C118552586 @default.
• W2056160771 hasConcept C126322002 @default.
• W2056160771 hasConcept C167135981 @default.
• W2056160771 hasConcept C194828623 @default.
• W2056160771 hasConcept C201903717 @default.
• W2056160771 hasConcept C2776914184 @default.
• W2056160771 hasConcept C2778384902 @default.
• W2056160771 hasConcept C2780724011 @default.
• W2056160771 hasConcept C2781195455 @default.
• W2056160771 hasConcept C58471807 @default.
• W2056160771 hasConcept C71924100 @default.
• W2056160771 hasConcept C72563966 @default.
• W2056160771 hasConcept C76318530 @default.
• W2056160771 hasConceptScore W2056160771C118552586 @default.
• W2056160771 hasConceptScore W2056160771C126322002 @default.
• W2056160771 hasConceptScore W2056160771C167135981 @default.
• W2056160771 hasConceptScore W2056160771C194828623 @default.
• W2056160771 hasConceptScore W2056160771C201903717 @default.
• W2056160771 hasConceptScore W2056160771C2776914184 @default.
• W2056160771 hasConceptScore W2056160771C2778384902 @default.
• W2056160771 hasConceptScore W2056160771C2780724011 @default.

• next