FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056179629> ?p ?o ?g. }

• W2056179629 endingPage "3327" @default.
• W2056179629 startingPage "3324" @default.
• W2056179629 abstract "Olfactory receptor (OR) genes constitute the basis for the sense of smell and are encoded by the largest mammalian gene superfamily of >1,000 genes. In humans, >60% of these are pseudogenes. In contrast, the mouse OR repertoire, although of roughly equal size, contains only approximately 20% pseudogenes. We asked whether the high fraction of nonfunctional OR genes is specific to humans or is a common feature of all primates. To this end, we have compared the sequences of 50 human OR coding regions, regardless of their functional annotations, to those of their putative orthologs in chimpanzees, gorillas, orangutans, and rhesus macaques. We found that humans have accumulated mutations that disrupt OR coding regions roughly 4-fold faster than any other species sampled. As a consequence, the fraction of OR pseudogenes in humans is almost twice as high as in the non-human primates, suggesting a human-specific process of OR gene disruption, likely due to a reduced chemosensory dependence relative to apes." @default.
• W2056179629 created "2016-06-24" @default.
• W2056179629 creator A5012216367 @default.
• W2056179629 creator A5014642082 @default.
• W2056179629 creator A5033532966 @default.
• W2056179629 creator A5059866150 @default.
• W2056179629 date "2003-02-28" @default.
• W2056179629 modified "2023-10-07" @default.
• W2056179629 title "Human specific loss of olfactory receptor genes" @default.
• W2056179629 cites W1479720172 @default.
• W2056179629 cites W1543325520 @default.
• W2056179629 cites W1594381616 @default.
• W2056179629 cites W1603858169 @default.
• W2056179629 cites W1984400584 @default.
• W2056179629 cites W1984780717 @default.
• W2056179629 cites W2032588711 @default.
• W2056179629 cites W2037055206 @default.
• W2056179629 cites W2052594204 @default.
• W2056179629 cites W2076799720 @default.
• W2056179629 cites W2084629681 @default.
• W2056179629 cites W2097186487 @default.
• W2056179629 cites W2101841137 @default.
• W2056179629 cites W2105489747 @default.
• W2056179629 cites W2112704704 @default.
• W2056179629 cites W2119632499 @default.
• W2056179629 cites W2122360349 @default.
• W2056179629 cites W2138777912 @default.
• W2056179629 cites W2143232398 @default.
• W2056179629 cites W2147555418 @default.
• W2056179629 cites W2158714788 @default.
• W2056179629 cites W2161240304 @default.
• W2056179629 cites W2164101639 @default.
• W2056179629 cites W2171421713 @default.
• W2056179629 cites W4232897314 @default.
• W2056179629 cites W4254828171 @default.
• W2056179629 doi "https://doi.org/10.1073/pnas.0535697100" @default.
• W2056179629 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/152291" @default.
• W2056179629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12612342" @default.
• W2056179629 hasPublicationYear "2003" @default.
• W2056179629 type Work @default.
• W2056179629 sameAs 2056179629 @default.
• W2056179629 citedByCount "248" @default.
• W2056179629 countsByYear W20561796292012 @default.
• W2056179629 countsByYear W20561796292013 @default.
• W2056179629 countsByYear W20561796292014 @default.
• W2056179629 countsByYear W20561796292015 @default.
• W2056179629 countsByYear W20561796292016 @default.
• W2056179629 countsByYear W20561796292017 @default.
• W2056179629 countsByYear W20561796292018 @default.
• W2056179629 countsByYear W20561796292019 @default.
• W2056179629 countsByYear W20561796292020 @default.
• W2056179629 countsByYear W20561796292021 @default.
• W2056179629 countsByYear W20561796292022 @default.
• W2056179629 countsByYear W20561796292023 @default.
• W2056179629 crossrefType "journal-article" @default.
• W2056179629 hasAuthorship W2056179629A5012216367 @default.
• W2056179629 hasAuthorship W2056179629A5014642082 @default.
• W2056179629 hasAuthorship W2056179629A5033532966 @default.
• W2056179629 hasAuthorship W2056179629A5059866150 @default.
• W2056179629 hasBestOaLocation W20561796291 @default.
• W2056179629 hasConcept C104317684 @default.
• W2056179629 hasConcept C121332964 @default.
• W2056179629 hasConcept C141231307 @default.
• W2056179629 hasConcept C170493617 @default.
• W2056179629 hasConcept C24890656 @default.
• W2056179629 hasConcept C2778473898 @default.
• W2056179629 hasConcept C2779980732 @default.
• W2056179629 hasConcept C34957205 @default.
• W2056179629 hasConcept C54355233 @default.
• W2056179629 hasConcept C78458016 @default.
• W2056179629 hasConcept C86803240 @default.
• W2056179629 hasConcept C91779695 @default.
• W2056179629 hasConceptScore W2056179629C104317684 @default.
• W2056179629 hasConceptScore W2056179629C121332964 @default.
• W2056179629 hasConceptScore W2056179629C141231307 @default.
• W2056179629 hasConceptScore W2056179629C170493617 @default.
• W2056179629 hasConceptScore W2056179629C24890656 @default.
• W2056179629 hasConceptScore W2056179629C2778473898 @default.
• W2056179629 hasConceptScore W2056179629C2779980732 @default.
• W2056179629 hasConceptScore W2056179629C34957205 @default.
• W2056179629 hasConceptScore W2056179629C54355233 @default.
• W2056179629 hasConceptScore W2056179629C78458016 @default.
• W2056179629 hasConceptScore W2056179629C86803240 @default.
• W2056179629 hasConceptScore W2056179629C91779695 @default.
• W2056179629 hasIssue "6" @default.
• W2056179629 hasLocation W20561796291 @default.
• W2056179629 hasLocation W20561796292 @default.
• W2056179629 hasLocation W20561796293 @default.
• W2056179629 hasLocation W20561796294 @default.
• W2056179629 hasOpenAccess W2056179629 @default.
• W2056179629 hasPrimaryLocation W20561796291 @default.
• W2056179629 hasRelatedWork W1977805690 @default.
• W2056179629 hasRelatedWork W1996567471 @default.
• W2056179629 hasRelatedWork W2001238294 @default.
• W2056179629 hasRelatedWork W2003343781 @default.
• W2056179629 hasRelatedWork W2028870911 @default.
• W2056179629 hasRelatedWork W2036653910 @default.
• W2056179629 hasRelatedWork W2063521569 @default.

• next