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• W2056185087 abstract "Here we developed a simple set-and-mix assay to perform high-throughput screening of protein kinase A (PKA) inhibitors from the LOPAC 1280 compound library. This assay is based on the color change of gold nanoparticles on aggregation induced by a cationic substrate peptide as coagulant. In spite of the simplicity of this assay system, this assay can be applied to drug screening based on cellular kinases. We successfully found several highly active inhibitors, including compounds that have not been reported before." @default.
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• W2056185087 date "2011-11-01" @default.
• W2056185087 modified "2023-10-16" @default.
• W2056185087 title "A simple set-and-mix assay for screening of protein kinase inhibitors in cell lysates" @default.
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• W2056185087 doi "https://doi.org/10.1016/j.ab.2011.06.041" @default.
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