FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056190491> ?p ?o ?g. }

• W2056190491 endingPage "211" @default.
• W2056190491 startingPage "206" @default.
• W2056190491 abstract "Diabetes mellitus (DM)-associated ED is predominantly due to neurovascular dysfunction mediated by nitric oxide (NO) suppression. Panax notoginseng saponins (PNS) are widely used for treating cardiovascular disease in China. The aim of this study was to evaluate the effects of PNS on penile erection and corpus cavernosum tissues in rats with diabetes-associated ED. Four weeks after PNS treatment, erectile function was assessed by intracavernous pressure (ICP) and mean arterial pressure (MAP) measurements. The level of NO, cyclic guanosine monophosphate (cGMP) and advanced glycation end products (AGEs) in cavernous tissue were assessed. Immunohistochemical staining and TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) were performed for detecting endothelial NO synthase (eNOS) and apoptosis, respectively. The results show that ICP/MAP ratio was significantly increased in high-dose (150 mg kg−1 per day) PNS-treated group compared with the diabetic ED untreated group (DM group). Compared with the untreated group, the expression of eNOS and the levels of NO and cGMP were increased in the PNS-treated groups. Moreover, apoptosis was markedly decreased in the group that received 150 mg kg−1 per day of PNS. These results suggest that PNS may be used for improving the ED in diabetic rats via the NO/cGMP pathway and restores the function of endothelium in corpus cavernosum." @default.
• W2056190491 created "2016-06-24" @default.
• W2056190491 creator A5071441776 @default.
• W2056190491 creator A5080568314 @default.
• W2056190491 date "2013-04-18" @default.
• W2056190491 modified "2023-09-23" @default.
• W2056190491 title "Panax notoginseng saponins improve the erectile dysfunction in diabetic rats by protecting the endothelial function of the penile corpus cavernosum" @default.
• W2056190491 cites W1605698794 @default.
• W2056190491 cites W1686916056 @default.
• W2056190491 cites W1836107361 @default.
• W2056190491 cites W1940926855 @default.
• W2056190491 cites W1966234811 @default.
• W2056190491 cites W1979521526 @default.
• W2056190491 cites W1980387889 @default.
• W2056190491 cites W1983149972 @default.
• W2056190491 cites W1986607628 @default.
• W2056190491 cites W1989028029 @default.
• W2056190491 cites W2007880055 @default.
• W2056190491 cites W2011023954 @default.
• W2056190491 cites W2012987222 @default.
• W2056190491 cites W2020503772 @default.
• W2056190491 cites W2022142901 @default.
• W2056190491 cites W2024563747 @default.
• W2056190491 cites W2026740190 @default.
• W2056190491 cites W2029190339 @default.
• W2056190491 cites W2034865357 @default.
• W2056190491 cites W2042113238 @default.
• W2056190491 cites W2046505242 @default.
• W2056190491 cites W2047623201 @default.
• W2056190491 cites W2049801272 @default.
• W2056190491 cites W2063069271 @default.
• W2056190491 cites W2072679381 @default.
• W2056190491 cites W2073731426 @default.
• W2056190491 cites W2080185912 @default.
• W2056190491 cites W2089172717 @default.
• W2056190491 cites W2098799717 @default.
• W2056190491 cites W2122664798 @default.
• W2056190491 cites W2128049884 @default.
• W2056190491 cites W2138414144 @default.
• W2056190491 cites W2153490891 @default.
• W2056190491 cites W2161440623 @default.
• W2056190491 cites W3184768937 @default.
• W2056190491 doi "https://doi.org/10.1038/ijir.2013.19" @default.
• W2056190491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23595104" @default.
• W2056190491 hasPublicationYear "2013" @default.
• W2056190491 type Work @default.
• W2056190491 sameAs 2056190491 @default.
• W2056190491 citedByCount "18" @default.
• W2056190491 countsByYear W20561904912014 @default.
• W2056190491 countsByYear W20561904912015 @default.
• W2056190491 countsByYear W20561904912016 @default.
• W2056190491 countsByYear W20561904912017 @default.
• W2056190491 countsByYear W20561904912018 @default.
• W2056190491 countsByYear W20561904912019 @default.
• W2056190491 countsByYear W20561904912020 @default.
• W2056190491 countsByYear W20561904912021 @default.
• W2056190491 countsByYear W20561904912023 @default.
• W2056190491 crossrefType "journal-article" @default.
• W2056190491 hasAuthorship W2056190491A5071441776 @default.
• W2056190491 hasAuthorship W2056190491A5080568314 @default.
• W2056190491 hasBestOaLocation W20561904911 @default.
• W2056190491 hasConcept C126322002 @default.
• W2056190491 hasConcept C134018914 @default.
• W2056190491 hasConcept C142724271 @default.
• W2056190491 hasConcept C154113507 @default.
• W2056190491 hasConcept C196795494 @default.
• W2056190491 hasConcept C204232928 @default.
• W2056190491 hasConcept C204787440 @default.
• W2056190491 hasConcept C2777622882 @default.
• W2056190491 hasConcept C2778326061 @default.
• W2056190491 hasConcept C2778509035 @default.
• W2056190491 hasConcept C2779929075 @default.
• W2056190491 hasConcept C2780994212 @default.
• W2056190491 hasConcept C2781212864 @default.
• W2056190491 hasConcept C519581460 @default.
• W2056190491 hasConcept C555293320 @default.
• W2056190491 hasConcept C71924100 @default.
• W2056190491 hasConceptScore W2056190491C126322002 @default.
• W2056190491 hasConceptScore W2056190491C134018914 @default.
• W2056190491 hasConceptScore W2056190491C142724271 @default.
• W2056190491 hasConceptScore W2056190491C154113507 @default.
• W2056190491 hasConceptScore W2056190491C196795494 @default.
• W2056190491 hasConceptScore W2056190491C204232928 @default.
• W2056190491 hasConceptScore W2056190491C204787440 @default.
• W2056190491 hasConceptScore W2056190491C2777622882 @default.
• W2056190491 hasConceptScore W2056190491C2778326061 @default.
• W2056190491 hasConceptScore W2056190491C2778509035 @default.
• W2056190491 hasConceptScore W2056190491C2779929075 @default.
• W2056190491 hasConceptScore W2056190491C2780994212 @default.
• W2056190491 hasConceptScore W2056190491C2781212864 @default.
• W2056190491 hasConceptScore W2056190491C519581460 @default.
• W2056190491 hasConceptScore W2056190491C555293320 @default.
• W2056190491 hasConceptScore W2056190491C71924100 @default.
• W2056190491 hasIssue "6" @default.
• W2056190491 hasLocation W20561904911 @default.
• W2056190491 hasLocation W20561904912 @default.
• W2056190491 hasOpenAccess W2056190491 @default.
• W2056190491 hasPrimaryLocation W20561904911 @default.

• next