Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056201054> ?p ?o ?g. }
- W2056201054 endingPage "81" @default.
- W2056201054 startingPage "71" @default.
- W2056201054 abstract "Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental abnormalities characterized by stereotypical communicative and social impairments, affecting 1 in 88 children in the United States. Both genetic and environmental factors contribute to the etiology of ASD. Autistic traits may be part of features associated with certain syndromes or the sole clinical presentation. Due to extreme heterogeneity and variable expressivity of the condition, clinical diagnosis and management have been challenging. Major advances in genomic technologies, computing power, and bioinformatics analyses have resulted in the accelerated discovery of novel genes and risk loci associated with both inherited and sporadic forms of ASD. Pathogenic genetic defects related to ASD range from single nucleotide variation to gross chromosomal abnormalities. In this review, we first summarize the current understanding of the genetic etiology of ASD; we then discuss how genetic diagnostics may influence the management and genetic counseling of ASD; and finally, we outline the strategy to integrate genetic tests into clinical care of children with ASD. We hope to inform primary care pediatricians and clinical genetic specialists how recent advances in the genetic research of ASD have been translated into clinical genetic testing for patients." @default.
- W2056201054 created "2016-06-24" @default.
- W2056201054 creator A5010157316 @default.
- W2056201054 creator A5082554849 @default.
- W2056201054 date "2014-03-14" @default.
- W2056201054 modified "2023-10-16" @default.
- W2056201054 title "Advances in Genetic Diagnosis of Autism Spectrum Disorders" @default.
- W2056201054 cites W125619285 @default.
- W2056201054 cites W1571662784 @default.
- W2056201054 cites W1598430865 @default.
- W2056201054 cites W1971321176 @default.
- W2056201054 cites W1974398566 @default.
- W2056201054 cites W1975890560 @default.
- W2056201054 cites W1975934382 @default.
- W2056201054 cites W1976671705 @default.
- W2056201054 cites W1978075999 @default.
- W2056201054 cites W1983953225 @default.
- W2056201054 cites W1988670106 @default.
- W2056201054 cites W1992315372 @default.
- W2056201054 cites W1995809507 @default.
- W2056201054 cites W1997070346 @default.
- W2056201054 cites W1997458019 @default.
- W2056201054 cites W1997714374 @default.
- W2056201054 cites W2000391750 @default.
- W2056201054 cites W2003655400 @default.
- W2056201054 cites W2005809131 @default.
- W2056201054 cites W2007282648 @default.
- W2056201054 cites W2015524830 @default.
- W2056201054 cites W2017766172 @default.
- W2056201054 cites W2020675188 @default.
- W2056201054 cites W2021856717 @default.
- W2056201054 cites W2024663595 @default.
- W2056201054 cites W2035017299 @default.
- W2056201054 cites W2038561863 @default.
- W2056201054 cites W2040026415 @default.
- W2056201054 cites W2047545454 @default.
- W2056201054 cites W2052401787 @default.
- W2056201054 cites W2063840478 @default.
- W2056201054 cites W2066219729 @default.
- W2056201054 cites W2076055965 @default.
- W2056201054 cites W2082881737 @default.
- W2056201054 cites W2085198610 @default.
- W2056201054 cites W2087547434 @default.
- W2056201054 cites W2089927164 @default.
- W2056201054 cites W2093973786 @default.
- W2056201054 cites W2094543961 @default.
- W2056201054 cites W2098000677 @default.
- W2056201054 cites W2102837197 @default.
- W2056201054 cites W2104838801 @default.
- W2056201054 cites W2107083291 @default.
- W2056201054 cites W2108210377 @default.
- W2056201054 cites W2114107709 @default.
- W2056201054 cites W2114378461 @default.
- W2056201054 cites W2117381227 @default.
- W2056201054 cites W2117782292 @default.
- W2056201054 cites W2118352176 @default.
- W2056201054 cites W2119315359 @default.
- W2056201054 cites W2119907069 @default.
- W2056201054 cites W2124284171 @default.
- W2056201054 cites W2124761086 @default.
- W2056201054 cites W2126467245 @default.
- W2056201054 cites W2127003470 @default.
- W2056201054 cites W2127634492 @default.
- W2056201054 cites W2129279571 @default.
- W2056201054 cites W2129873641 @default.
- W2056201054 cites W2131104106 @default.
- W2056201054 cites W2131587128 @default.
- W2056201054 cites W2133978628 @default.
- W2056201054 cites W2134259328 @default.
- W2056201054 cites W2134335825 @default.
- W2056201054 cites W2140383855 @default.
- W2056201054 cites W2141704631 @default.
- W2056201054 cites W2142677693 @default.
- W2056201054 cites W2142745778 @default.
- W2056201054 cites W2143871914 @default.
- W2056201054 cites W2150648630 @default.
- W2056201054 cites W2156712014 @default.
- W2056201054 cites W2160329471 @default.
- W2056201054 cites W2162066558 @default.
- W2056201054 cites W2167684047 @default.
- W2056201054 cites W2167740461 @default.
- W2056201054 cites W2169544120 @default.
- W2056201054 cites W2415400009 @default.
- W2056201054 cites W4234249493 @default.
- W2056201054 doi "https://doi.org/10.1007/s40124-014-0042-z" @default.
- W2056201054 hasPublicationYear "2014" @default.
- W2056201054 type Work @default.
- W2056201054 sameAs 2056201054 @default.
- W2056201054 citedByCount "3" @default.
- W2056201054 countsByYear W20562010542014 @default.
- W2056201054 countsByYear W20562010542015 @default.
- W2056201054 countsByYear W20562010542022 @default.
- W2056201054 crossrefType "journal-article" @default.
- W2056201054 hasAuthorship W2056201054A5010157316 @default.
- W2056201054 hasAuthorship W2056201054A5082554849 @default.
- W2056201054 hasBestOaLocation W20562010541 @default.
- W2056201054 hasConcept C118552586 @default.
- W2056201054 hasConcept C121332964 @default.