Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056210827> ?p ?o ?g. }
- W2056210827 endingPage "36" @default.
- W2056210827 startingPage "29" @default.
- W2056210827 abstract "Many computational tools routinely used in chemistry could successfully be applied to the biosciences since protein-protein and protein-ligand interactions are governed by the laws of chemistry. This paper shows that it is possible to extend the use of existing computational tools from their traditional application field (e.g. chemistry) to culturally-related research areas by the implementation of simple but well-designed utilities. In particular, a computational strategy obtained by combining GRID (the program originally designed by Peter Goodford, and now distributed by Molecular Discovery Ltd.) and BIOCUBE4mf (an application freely available at www.casmedchem.unito.it) was used to a) characterize the surface properties of the cavity of the Bacillus anthracis protective antigen heptameric prepore; b) suggest how to design mutagenesis experiments; c) quantitatively show the selectivity of the KvAP channel for K(+) over Na(+) ions and d) rationalize the pharmacokinetic behavior of 1,4-DHP third-generation drugs." @default.
- W2056210827 created "2016-06-24" @default.
- W2056210827 creator A5011354227 @default.
- W2056210827 creator A5063653917 @default.
- W2056210827 date "2009-01-05" @default.
- W2056210827 modified "2023-10-16" @default.
- W2056210827 title "How to Extend the Use of Grid‐Based Interaction Energy Maps from Chemistry to Biotopics" @default.
- W2056210827 cites W1492227883 @default.
- W2056210827 cites W1494632364 @default.
- W2056210827 cites W1543604915 @default.
- W2056210827 cites W1759440238 @default.
- W2056210827 cites W1965620022 @default.
- W2056210827 cites W1968138630 @default.
- W2056210827 cites W1989433812 @default.
- W2056210827 cites W1994424166 @default.
- W2056210827 cites W2000861116 @default.
- W2056210827 cites W2002609131 @default.
- W2056210827 cites W2010955856 @default.
- W2056210827 cites W2014123957 @default.
- W2056210827 cites W2015148410 @default.
- W2056210827 cites W2015461838 @default.
- W2056210827 cites W2019686608 @default.
- W2056210827 cites W2044898030 @default.
- W2056210827 cites W2079212402 @default.
- W2056210827 cites W2091758060 @default.
- W2056210827 cites W2094691530 @default.
- W2056210827 cites W2095192370 @default.
- W2056210827 cites W2156071488 @default.
- W2056210827 doi "https://doi.org/10.1002/cmdc.200800259" @default.
- W2056210827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19085992" @default.
- W2056210827 hasPublicationYear "2009" @default.
- W2056210827 type Work @default.
- W2056210827 sameAs 2056210827 @default.
- W2056210827 citedByCount "6" @default.
- W2056210827 countsByYear W20562108272015 @default.
- W2056210827 crossrefType "journal-article" @default.
- W2056210827 hasAuthorship W2056210827A5011354227 @default.
- W2056210827 hasAuthorship W2056210827A5063653917 @default.
- W2056210827 hasConcept C104317684 @default.
- W2056210827 hasConcept C147597530 @default.
- W2056210827 hasConcept C16318435 @default.
- W2056210827 hasConcept C171250308 @default.
- W2056210827 hasConcept C185592680 @default.
- W2056210827 hasConcept C187691185 @default.
- W2056210827 hasConcept C191120209 @default.
- W2056210827 hasConcept C192562407 @default.
- W2056210827 hasConcept C202444582 @default.
- W2056210827 hasConcept C2524010 @default.
- W2056210827 hasConcept C2780239966 @default.
- W2056210827 hasConcept C2993809622 @default.
- W2056210827 hasConcept C33923547 @default.
- W2056210827 hasConcept C41008148 @default.
- W2056210827 hasConcept C501734568 @default.
- W2056210827 hasConcept C523546767 @default.
- W2056210827 hasConcept C54355233 @default.
- W2056210827 hasConcept C55493867 @default.
- W2056210827 hasConcept C70721500 @default.
- W2056210827 hasConcept C86803240 @default.
- W2056210827 hasConcept C9652623 @default.
- W2056210827 hasConceptScore W2056210827C104317684 @default.
- W2056210827 hasConceptScore W2056210827C147597530 @default.
- W2056210827 hasConceptScore W2056210827C16318435 @default.
- W2056210827 hasConceptScore W2056210827C171250308 @default.
- W2056210827 hasConceptScore W2056210827C185592680 @default.
- W2056210827 hasConceptScore W2056210827C187691185 @default.
- W2056210827 hasConceptScore W2056210827C191120209 @default.
- W2056210827 hasConceptScore W2056210827C192562407 @default.
- W2056210827 hasConceptScore W2056210827C202444582 @default.
- W2056210827 hasConceptScore W2056210827C2524010 @default.
- W2056210827 hasConceptScore W2056210827C2780239966 @default.
- W2056210827 hasConceptScore W2056210827C2993809622 @default.
- W2056210827 hasConceptScore W2056210827C33923547 @default.
- W2056210827 hasConceptScore W2056210827C41008148 @default.
- W2056210827 hasConceptScore W2056210827C501734568 @default.
- W2056210827 hasConceptScore W2056210827C523546767 @default.
- W2056210827 hasConceptScore W2056210827C54355233 @default.
- W2056210827 hasConceptScore W2056210827C55493867 @default.
- W2056210827 hasConceptScore W2056210827C70721500 @default.
- W2056210827 hasConceptScore W2056210827C86803240 @default.
- W2056210827 hasConceptScore W2056210827C9652623 @default.
- W2056210827 hasIssue "1" @default.
- W2056210827 hasLocation W20562108271 @default.
- W2056210827 hasLocation W20562108272 @default.
- W2056210827 hasOpenAccess W2056210827 @default.
- W2056210827 hasPrimaryLocation W20562108271 @default.
- W2056210827 hasRelatedWork W129091060 @default.
- W2056210827 hasRelatedWork W2160425906 @default.
- W2056210827 hasRelatedWork W2348896848 @default.
- W2056210827 hasRelatedWork W2352349437 @default.
- W2056210827 hasRelatedWork W2354568776 @default.
- W2056210827 hasRelatedWork W2380963126 @default.
- W2056210827 hasRelatedWork W2389875415 @default.
- W2056210827 hasRelatedWork W2748952813 @default.
- W2056210827 hasRelatedWork W2899084033 @default.
- W2056210827 hasRelatedWork W1544908136 @default.
- W2056210827 hasVolume "4" @default.
- W2056210827 isParatext "false" @default.
- W2056210827 isRetracted "false" @default.