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- W2056232542 abstract "Abstract 1. 1. Pairs of glomerular and tubular basement membrane preparations were isolated from kidney cortex of cattle, pig, sheep, horse, man and rat. Tubular basement membranes were isolated from rabbit kidney cortex. 2. 2. Purity of preparations was established with light- and electron microscopy and by estimating total phosphorus content. 3. 3. Marked species dependent variations were found for the following components and ratios: with glomerular basement membranes for the contents of aspartic acid, threonine, serine, glycine, tyrosine and hexosamines; with tubular basement membranes for the contents of alanine, isoleucine, fucose and mannose; with both types of basement membranes for the contents of histidine, glucose and galactose and the ratios of hydroxylated to nonhydroxylated proline and lysine residues, but not for the ratio of 4-hydroxyproline to hydroxylysine. 4. 4. Comparison of glomerular and tubular basement membranes as pairs from individuals shows differences in all species. As a common phenomenon, the glomerular basement membrane preparations of the six species contain about twice as much neuraminic acids and more mannose and hexosamines than their tubular counterparts. 5. 5. Observed differences may be related to variations in antigenic properties of the different types of renal basement membranes." @default.
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- W2056232542 date "1981-01-01" @default.
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- W2056232542 title "Chemical characterization of glomerular and tubular basement membranes of various mammalian species" @default.
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- W2056232542 doi "https://doi.org/10.1016/0305-0491(81)90176-0" @default.
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