Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056252598> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2056252598 endingPage "A23" @default.
- W2056252598 startingPage "A23" @default.
- W2056252598 abstract "Background The BRAF p.V600E somatic mutation is present in approximately 10-20% of unselected colorectal cancer (CRC) and 30% -75% of CRCs demonstrating high levels of microsatellite instability (MSI-H). Currently, testing for the BRAF p.V600E mutation is undertaken to exclude Lynch syndrome in MSI-H CRCs that demonstrate loss of the MLH1 and PMS2 proteins by IHC. However, recent evidence suggests that the BRAF p. V600E mutation is associated with a familial predisposition to serrated neoplasia, an increased risk of CRC and possibly extra-colonic cancers in relatives. The aim of this study was to determine 1) if early-onset CRC with the BRAF p.V600E mutation is associated with a family history of CRC, and 2) if pathological features of BRAF positive CRCs associate with CRC development in relatives." @default.
- W2056252598 created "2016-06-24" @default.
- W2056252598 creator A5027617938 @default.
- W2056252598 creator A5030032251 @default.
- W2056252598 creator A5030770731 @default.
- W2056252598 creator A5051077025 @default.
- W2056252598 creator A5053217861 @default.
- W2056252598 creator A5055927969 @default.
- W2056252598 creator A5062756156 @default.
- W2056252598 creator A5066347403 @default.
- W2056252598 creator A5067660727 @default.
- W2056252598 creator A5080782409 @default.
- W2056252598 creator A5087299335 @default.
- W2056252598 creator A5088734778 @default.
- W2056252598 creator A5090508414 @default.
- W2056252598 date "2012-01-01" @default.
- W2056252598 modified "2023-10-10" @default.
- W2056252598 title "The relationship between the BRAF p.V600E mutation and a family history of CRC in the early-onset CRC cases from the Australasian Colon Cancer Family Study" @default.
- W2056252598 doi "https://doi.org/10.1186/1897-4287-10-s2-a23" @default.
- W2056252598 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3326696" @default.
- W2056252598 hasPublicationYear "2012" @default.
- W2056252598 type Work @default.
- W2056252598 sameAs 2056252598 @default.
- W2056252598 citedByCount "0" @default.
- W2056252598 crossrefType "journal-article" @default.
- W2056252598 hasAuthorship W2056252598A5027617938 @default.
- W2056252598 hasAuthorship W2056252598A5030032251 @default.
- W2056252598 hasAuthorship W2056252598A5030770731 @default.
- W2056252598 hasAuthorship W2056252598A5051077025 @default.
- W2056252598 hasAuthorship W2056252598A5053217861 @default.
- W2056252598 hasAuthorship W2056252598A5055927969 @default.
- W2056252598 hasAuthorship W2056252598A5062756156 @default.
- W2056252598 hasAuthorship W2056252598A5066347403 @default.
- W2056252598 hasAuthorship W2056252598A5067660727 @default.
- W2056252598 hasAuthorship W2056252598A5080782409 @default.
- W2056252598 hasAuthorship W2056252598A5087299335 @default.
- W2056252598 hasAuthorship W2056252598A5088734778 @default.
- W2056252598 hasAuthorship W2056252598A5090508414 @default.
- W2056252598 hasBestOaLocation W20562525981 @default.
- W2056252598 hasConcept C104317684 @default.
- W2056252598 hasConcept C121608353 @default.
- W2056252598 hasConcept C126322002 @default.
- W2056252598 hasConcept C143998085 @default.
- W2056252598 hasConcept C2781179581 @default.
- W2056252598 hasConcept C47042493 @default.
- W2056252598 hasConcept C501734568 @default.
- W2056252598 hasConcept C526805850 @default.
- W2056252598 hasConcept C54355233 @default.
- W2056252598 hasConcept C71924100 @default.
- W2056252598 hasConcept C86803240 @default.
- W2056252598 hasConceptScore W2056252598C104317684 @default.
- W2056252598 hasConceptScore W2056252598C121608353 @default.
- W2056252598 hasConceptScore W2056252598C126322002 @default.
- W2056252598 hasConceptScore W2056252598C143998085 @default.
- W2056252598 hasConceptScore W2056252598C2781179581 @default.
- W2056252598 hasConceptScore W2056252598C47042493 @default.
- W2056252598 hasConceptScore W2056252598C501734568 @default.
- W2056252598 hasConceptScore W2056252598C526805850 @default.
- W2056252598 hasConceptScore W2056252598C54355233 @default.
- W2056252598 hasConceptScore W2056252598C71924100 @default.
- W2056252598 hasConceptScore W2056252598C86803240 @default.
- W2056252598 hasIssue "Suppl 2" @default.
- W2056252598 hasLocation W20562525981 @default.
- W2056252598 hasLocation W20562525982 @default.
- W2056252598 hasLocation W20562525983 @default.
- W2056252598 hasLocation W20562525984 @default.
- W2056252598 hasOpenAccess W2056252598 @default.
- W2056252598 hasPrimaryLocation W20562525981 @default.
- W2056252598 hasRelatedWork W1978333394 @default.
- W2056252598 hasRelatedWork W2007665586 @default.
- W2056252598 hasRelatedWork W2074686980 @default.
- W2056252598 hasRelatedWork W2107943234 @default.
- W2056252598 hasRelatedWork W2108891940 @default.
- W2056252598 hasRelatedWork W2344258046 @default.
- W2056252598 hasRelatedWork W2392730113 @default.
- W2056252598 hasRelatedWork W2468272264 @default.
- W2056252598 hasRelatedWork W2500804473 @default.
- W2056252598 hasRelatedWork W3004259476 @default.
- W2056252598 hasVolume "10" @default.
- W2056252598 isParatext "false" @default.
- W2056252598 isRetracted "false" @default.
- W2056252598 magId "2056252598" @default.
- W2056252598 workType "article" @default.