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- W2056268931 abstract "Introduction Non-invasive transcutaneous spinal direct current stimulation (tsDCS) induces changes in spinal cord function in humans (Cogiamanian et al., 2012). The physiological mechanisms underlying these changes however remain speculative. A relevant issue to better understand this innovative non-invasive neuromodulation technique is the estimation of the spatial distribution of the current density in the spinal cord during tsDCS. Objective To evaluate the current density ( J ) induced by dorsal tsDCS in the spinal cord using electromagnetics computational techniques applied to realistic human models of different age and gender. Materials and methods The computation was conducted using the simulation platform SEMCAD X (Schmid & Partner Engineering AG, Zurich, Switzerland) solving the Laplace equation. Three realistic human models of the Virtual Family (Christ et al., 2010) were used. The models are based on high resolution magnetic resonance images of healthy volunteers (a 26-years-old female adult model Ella; a 34years-old male adult model Duke; an 11years old female adolescent model Billie). The models consist of up to 77 different tissues, the dielectric properties of which were assigned on the basis of the data at low frequency (Gabriel et al., 1996). In this preliminary study three electrode montages were modeled in which the anode was always over the spinal process of the tenth thoracic vertebra and the cathode was placed: (i) above the right deltoid (ii) over the umbilicus; (iii) over Cz. The injected current was 3mA. The electrodes were conductors within rectangular sponges. Results Preliminary data indicates that in the dorsal spinal cord below the stimulating electrode the peaks of J across the models are of 0.02 A/m 2 , 0.03 A/m 2 and 0.06 A/m 2 for the three electrode montages, respectively. Conclusion The electric field generated by tsDCS reaches the spinal cord at physiologically effective strength." @default.
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- W2056268931 date "2013-10-01" @default.
- W2056268931 modified "2023-09-28" @default.
- W2056268931 title "P 225. Computational models of current densities in transcutaneous spinal direct current stimulation (tsDCS)" @default.
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- W2056268931 doi "https://doi.org/10.1016/j.clinph.2013.04.302" @default.
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