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• W2056314285 abstract "We measured sICAM-1 in paired samples of serum and cerebrospinal fluid (CSF) from patients with an attack of multiple sclerosis (MS) (n=50) and patients with acute monosymptomatic optic neuritis (ON) as a possible first attack of MS were also included (n=25). Based on calculations of extended indices we found evidence of intrathecal synthesis of sICAM-1 both in patients with clinically definite MS and in patients with idiopathic ON compared to neurological control subjects. The amount of intrathecally synthesized sICAM-1 correlated significantly to the CSF leukocyte count and to the concentration of myelin basic protein in the CSF. The serum concentrations of sICAM-1 were not increased in patients with demyelinating disease compared to the neurological control subjects." @default.
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• W2056314285 date "1998-08-01" @default.
• W2056314285 modified "2023-10-05" @default.
• W2056314285 title "Soluble ICAM-1, demyelination, and inflammation in multiple sclerosis and acute optic neuritis" @default.
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• W2056314285 doi "https://doi.org/10.1016/s0165-5728(98)00103-9" @default.
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