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- W2056320072 abstract "Heat shock/chaperone protein (HSCP)–peptide complexes can access the cross-priming pathways of antigen presenting cells (APCs), and the gp96-associated peptides can be re-presented on APC MHC class I molecules to elicit CD8+ T cell activation. This immunological circuit is thought to provide the functional basis for HSCP function in tumor immunity. Recent findings identifying a ‘natural adjuvant’ function for HSCPs suggest complementary, or perhaps alternative, mechanisms of HSCP-mediated tumor rejection." @default.
- W2056320072 created "2016-06-24" @default.
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- W2056320072 date "2003-02-01" @default.
- W2056320072 modified "2023-09-25" @default.
- W2056320072 title "ISO: a critical evaluation of the role of peptides in heat shock/chaperone protein-mediated tumor rejection" @default.
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- W2056320072 doi "https://doi.org/10.1016/s0952791502000067" @default.
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