Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056334527> ?p ?o ?g. }
- W2056334527 endingPage "14" @default.
- W2056334527 startingPage "1" @default.
- W2056334527 abstract "In this brief review, we discuss immune tolerance as a factor that determines the magnitude and quality of serum antibody responses to HIV-1 infection and vaccination in the context of recent work. We propose that many conserved, neutralizing epitopes of HIV-1 are weakly immunogenic because they mimic host antigens. In consequence, B cells that strongly bind these determinants are removed by the physiological process of immune tolerance. This structural mimicry may represent a significant impediment to designing protective HIV-1 vaccines, but we note that several vaccine strategies may be able to mitigate this evolutionary adaptation of HIV and other microbial pathogens." @default.
- W2056334527 created "2016-06-24" @default.
- W2056334527 creator A5009040513 @default.
- W2056334527 creator A5051827275 @default.
- W2056334527 creator A5065001474 @default.
- W2056334527 date "2013-12-19" @default.
- W2056334527 modified "2023-10-16" @default.
- W2056334527 title "Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies" @default.
- W2056334527 cites W129650649 @default.
- W2056334527 cites W1480892076 @default.
- W2056334527 cites W1565279052 @default.
- W2056334527 cites W1591766096 @default.
- W2056334527 cites W1628484047 @default.
- W2056334527 cites W1893222585 @default.
- W2056334527 cites W1969130098 @default.
- W2056334527 cites W1969156908 @default.
- W2056334527 cites W1973231875 @default.
- W2056334527 cites W1974273518 @default.
- W2056334527 cites W1978398372 @default.
- W2056334527 cites W1979882766 @default.
- W2056334527 cites W1980322325 @default.
- W2056334527 cites W1984570470 @default.
- W2056334527 cites W1985145726 @default.
- W2056334527 cites W1989413225 @default.
- W2056334527 cites W1990152283 @default.
- W2056334527 cites W1991497659 @default.
- W2056334527 cites W1995466180 @default.
- W2056334527 cites W1997677784 @default.
- W2056334527 cites W2014334082 @default.
- W2056334527 cites W2016208323 @default.
- W2056334527 cites W2016453064 @default.
- W2056334527 cites W2021501950 @default.
- W2056334527 cites W2022890571 @default.
- W2056334527 cites W2025633900 @default.
- W2056334527 cites W2030816309 @default.
- W2056334527 cites W2034271713 @default.
- W2056334527 cites W2040878504 @default.
- W2056334527 cites W2048787904 @default.
- W2056334527 cites W2052937459 @default.
- W2056334527 cites W2054392131 @default.
- W2056334527 cites W2058416188 @default.
- W2056334527 cites W2063195211 @default.
- W2056334527 cites W2069047496 @default.
- W2056334527 cites W2070086938 @default.
- W2056334527 cites W2071380288 @default.
- W2056334527 cites W2076198413 @default.
- W2056334527 cites W2078913377 @default.
- W2056334527 cites W2081291921 @default.
- W2056334527 cites W2087293737 @default.
- W2056334527 cites W2089766500 @default.
- W2056334527 cites W2092658173 @default.
- W2056334527 cites W2093514748 @default.
- W2056334527 cites W2097594050 @default.
- W2056334527 cites W2105336865 @default.
- W2056334527 cites W2108513916 @default.
- W2056334527 cites W2109229894 @default.
- W2056334527 cites W2109562998 @default.
- W2056334527 cites W2112545544 @default.
- W2056334527 cites W2113595673 @default.
- W2056334527 cites W2125878189 @default.
- W2056334527 cites W2131039822 @default.
- W2056334527 cites W2132773138 @default.
- W2056334527 cites W2134803208 @default.
- W2056334527 cites W2135151522 @default.
- W2056334527 cites W2136489732 @default.
- W2056334527 cites W2139978152 @default.
- W2056334527 cites W2152440860 @default.
- W2056334527 cites W2159149406 @default.
- W2056334527 cites W2166740197 @default.
- W2056334527 cites W2167369293 @default.
- W2056334527 cites W2167455626 @default.
- W2056334527 cites W2171690009 @default.
- W2056334527 doi "https://doi.org/10.3390/vaccines2010001" @default.
- W2056334527 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4053940" @default.
- W2056334527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24932410" @default.
- W2056334527 hasPublicationYear "2013" @default.
- W2056334527 type Work @default.
- W2056334527 sameAs 2056334527 @default.
- W2056334527 citedByCount "21" @default.
- W2056334527 countsByYear W20563345272014 @default.
- W2056334527 countsByYear W20563345272015 @default.
- W2056334527 countsByYear W20563345272016 @default.
- W2056334527 countsByYear W20563345272017 @default.
- W2056334527 countsByYear W20563345272018 @default.
- W2056334527 countsByYear W20563345272019 @default.
- W2056334527 countsByYear W20563345272020 @default.
- W2056334527 countsByYear W20563345272022 @default.
- W2056334527 crossrefType "journal-article" @default.
- W2056334527 hasAuthorship W2056334527A5009040513 @default.
- W2056334527 hasAuthorship W2056334527A5051827275 @default.
- W2056334527 hasAuthorship W2056334527A5065001474 @default.
- W2056334527 hasBestOaLocation W20563345271 @default.
- W2056334527 hasConcept C139807058 @default.
- W2056334527 hasConcept C147483822 @default.
- W2056334527 hasConcept C151730666 @default.
- W2056334527 hasConcept C159047783 @default.
- W2056334527 hasConcept C159654299 @default.
- W2056334527 hasConcept C169760540 @default.