FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056361631> ?p ?o ?g. }

• W2056361631 endingPage "513" @default.
• W2056361631 startingPage "507" @default.
• W2056361631 abstract "In Brief Objective: To report the risk of metachronous colorectal neoplasia after colectomy for cancer in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. Summary background data: Patients meeting Amsterdam criteria for diagnosis of HNPCC have a lifetime colorectal cancer risk approaching 80%, and a metachronous cancer rate of approximately 25%. Therefore, when colon cancer is diagnosed, total rather than segmental colectomy is advocated. However, information about adenoma and carcinoma risk after index surgery is still underreported. Methods: A hereditary colorectal cancer database was reviewed for patients meeting Amsterdam criteria who underwent colectomy for cancer. Patient demographics, surgical management, and results of follow-up were recorded. Metachronous colorectal adenoma and carcinoma development were the primary end points. Results: A total of 296 patients (253 with segmental colectomy and 43 with total colectomy/ileorectal anastomosis) were analyzed. Of the 253 segmental colectomy patients, 221 (88%) had postoperative endoscopic surveillance with median follow-up of 104 months. In 74 patients (33%), 256 adenomas were detected, including 140 high-risk adenomas in 48 patients (22%). Fifty-five patients (25%) developed a second colorectal cancer at a median of 69 months after index surgery. Stages of the metachronous cancers were I-16, II-18, III-12, and IV-2. By comparison, 4 of 38 patients (11%) who underwent total colectomy developed subsequent high-risk adenomas and 3 (8%) developed metachronous cancer. Conclusions: Amsterdam patients undergoing partial colectomy have a high rate of metachronous high-risk adenomas and carcinomas. Total colectomy for the index cancer is the procedure of choice. For either surgical option, yearly endoscopic surveillance is essential to remove premalignant adenomas. Metachronous colorectal neoplasia risk after colectomy in hereditary nonpolyposis colorectal cancer remains incompletely defined. This study reports a 22% rate of high-risk adenomas and 25% rate of adenocarcinomas after segmental colectomy compared with 11% and 8% risk after a total colectomy and ileorectal anastomosis. Total colectomy is the preferred treatment for an index colon cancer in a patient with hereditary nonpolyposis colorectal cancer." @default.
• W2056361631 created "2016-06-24" @default.
• W2056361631 creator A5025398249 @default.
• W2056361631 creator A5026198545 @default.
• W2056361631 creator A5034386894 @default.
• W2056361631 creator A5035621447 @default.
• W2056361631 creator A5039079081 @default.
• W2056361631 creator A5058432973 @default.
• W2056361631 date "2010-09-01" @default.
• W2056361631 modified "2023-09-30" @default.
• W2056361631 title "Risk of Colorectal Adenoma and Carcinoma After Colectomy for Colorectal Cancer in Patients Meeting Amsterdam Criteria" @default.
• W2056361631 cites W1570562601 @default.
• W2056361631 cites W1981831407 @default.
• W2056361631 cites W1987284860 @default.
• W2056361631 cites W1992484513 @default.
• W2056361631 cites W2007812753 @default.
• W2056361631 cites W2010766084 @default.
• W2056361631 cites W2011409548 @default.
• W2056361631 cites W2030262663 @default.
• W2056361631 cites W2049695244 @default.
• W2056361631 cites W2068400231 @default.
• W2056361631 cites W2079819604 @default.
• W2056361631 cites W2096371251 @default.
• W2056361631 cites W2101995865 @default.
• W2056361631 cites W2102648946 @default.
• W2056361631 cites W2103547637 @default.
• W2056361631 cites W2112677111 @default.
• W2056361631 cites W2117221748 @default.
• W2056361631 cites W2118826912 @default.
• W2056361631 cites W2121057485 @default.
• W2056361631 cites W2124896165 @default.
• W2056361631 cites W2148025161 @default.
• W2056361631 cites W2156299764 @default.
• W2056361631 cites W2161989604 @default.
• W2056361631 cites W2330312275 @default.
• W2056361631 cites W61010407 @default.
• W2056361631 doi "https://doi.org/10.1097/sla.0b013e3181f20bd2" @default.
• W2056361631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20739851" @default.
• W2056361631 hasPublicationYear "2010" @default.
• W2056361631 type Work @default.
• W2056361631 sameAs 2056361631 @default.
• W2056361631 citedByCount "70" @default.
• W2056361631 countsByYear W20563616312012 @default.
• W2056361631 countsByYear W20563616312013 @default.
• W2056361631 countsByYear W20563616312014 @default.
• W2056361631 countsByYear W20563616312015 @default.
• W2056361631 countsByYear W20563616312016 @default.
• W2056361631 countsByYear W20563616312017 @default.
• W2056361631 countsByYear W20563616312018 @default.
• W2056361631 countsByYear W20563616312019 @default.
• W2056361631 countsByYear W20563616312020 @default.
• W2056361631 countsByYear W20563616312021 @default.
• W2056361631 countsByYear W20563616312022 @default.
• W2056361631 countsByYear W20563616312023 @default.
• W2056361631 crossrefType "journal-article" @default.
• W2056361631 hasAuthorship W2056361631A5025398249 @default.
• W2056361631 hasAuthorship W2056361631A5026198545 @default.
• W2056361631 hasAuthorship W2056361631A5034386894 @default.
• W2056361631 hasAuthorship W2056361631A5035621447 @default.
• W2056361631 hasAuthorship W2056361631A5039079081 @default.
• W2056361631 hasAuthorship W2056361631A5058432973 @default.
• W2056361631 hasConcept C121608353 @default.
• W2056361631 hasConcept C126322002 @default.
• W2056361631 hasConcept C141071460 @default.
• W2056361631 hasConcept C2776667177 @default.
• W2056361631 hasConcept C2777428134 @default.
• W2056361631 hasConcept C526805850 @default.
• W2056361631 hasConcept C61434518 @default.
• W2056361631 hasConcept C71924100 @default.
• W2056361631 hasConcept C90924648 @default.
• W2056361631 hasConceptScore W2056361631C121608353 @default.
• W2056361631 hasConceptScore W2056361631C126322002 @default.
• W2056361631 hasConceptScore W2056361631C141071460 @default.
• W2056361631 hasConceptScore W2056361631C2776667177 @default.
• W2056361631 hasConceptScore W2056361631C2777428134 @default.
• W2056361631 hasConceptScore W2056361631C526805850 @default.
• W2056361631 hasConceptScore W2056361631C61434518 @default.
• W2056361631 hasConceptScore W2056361631C71924100 @default.
• W2056361631 hasConceptScore W2056361631C90924648 @default.
• W2056361631 hasIssue "3" @default.
• W2056361631 hasLocation W20563616311 @default.
• W2056361631 hasLocation W20563616312 @default.
• W2056361631 hasOpenAccess W2056361631 @default.
• W2056361631 hasPrimaryLocation W20563616311 @default.
• W2056361631 hasRelatedWork W2002120878 @default.
• W2056361631 hasRelatedWork W2003938723 @default.
• W2056361631 hasRelatedWork W2047967234 @default.
• W2056361631 hasRelatedWork W2118496982 @default.
• W2056361631 hasRelatedWork W2364998975 @default.
• W2056361631 hasRelatedWork W2439875401 @default.
• W2056361631 hasRelatedWork W2531801821 @default.
• W2056361631 hasRelatedWork W3208701539 @default.
• W2056361631 hasRelatedWork W4238867864 @default.
• W2056361631 hasRelatedWork W2525756941 @default.
• W2056361631 hasVolume "252" @default.
• W2056361631 isParatext "false" @default.
• W2056361631 isRetracted "false" @default.
• W2056361631 magId "2056361631" @default.

• next