FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056366969> ?p ?o ?g. }

• W2056366969 endingPage "2958" @default.
• W2056366969 startingPage "2951" @default.
• W2056366969 abstract "Neisseria meningitidis serogroup C polysaccharide (PS C) was conjugated to serogroup B outer membrane vesicles (OMV) in order to test the possibility of obtaining a bivalent group B and C meningococcus vaccine. The conjugate and controls were injected intraperitoneally into groups of ten mice with boosters on days 14 and 28 after the primary immunization. The following groups were used as control: (i) PS C; (ii) PS C plus OMV; (iii) OMV; and (iv) saline. The serum collected on days 0, 14, 28 and 42 were tested by enzyme-linked immunosorbent assay (ELISA) for PS C and OMV, and by complement mediated bactericidal assay against serogroups B and C. ELISA for PS C as well as bactericidal titres against serogroup C meningococci of the conjugated vaccine increased eight-fold (ELISA) and 32 fold (bactericidal) after 42 days in comparison with the PS C control group. ELISA for OMV and bactericidal titre against serogroup B meningococci of the conjugate showed no significant difference in comparison with the OMV containing controls. Furthermore, Western Blot assay of the conjugate immune serum did not bind OMV class four protein which is related to the complement dependent antibody suppressor. The results indicate that the PS C-OMV conjugate could be a candidate for a bivalent vaccine toward serogroups B and C meningococci." @default.
• W2056366969 created "2016-06-24" @default.
• W2056366969 creator A5027441298 @default.
• W2056366969 creator A5036774958 @default.
• W2056366969 creator A5053713371 @default.
• W2056366969 creator A5061259130 @default.
• W2056366969 creator A5069295773 @default.
• W2056366969 creator A5069878139 @default.
• W2056366969 creator A5091050205 @default.
• W2056366969 date "1999-08-01" @default.
• W2056366969 modified "2023-10-05" @default.
• W2056366969 title "Neisseria meningitidis serogroup C polysaccharide and serogroup B outer membrane vesicle conjugate as a bivalent meningococcus vaccine candidate" @default.
• W2056366969 cites W1580023435 @default.
• W2056366969 cites W1904850674 @default.
• W2056366969 cites W1912692997 @default.
• W2056366969 cites W1979945579 @default.
• W2056366969 cites W1979986360 @default.
• W2056366969 cites W2013783824 @default.
• W2056366969 cites W2054495382 @default.
• W2056366969 cites W2079581642 @default.
• W2056366969 cites W2092484782 @default.
• W2056366969 cites W2094786954 @default.
• W2056366969 cites W2102152483 @default.
• W2056366969 cites W2119875145 @default.
• W2056366969 cites W2156339347 @default.
• W2056366969 cites W2160828078 @default.
• W2056366969 cites W2169253475 @default.
• W2056366969 cites W2317858883 @default.
• W2056366969 doi "https://doi.org/10.1016/s0264-410x(99)00177-2" @default.
• W2056366969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10462229" @default.
• W2056366969 hasPublicationYear "1999" @default.
• W2056366969 type Work @default.
• W2056366969 sameAs 2056366969 @default.
• W2056366969 citedByCount "17" @default.
• W2056366969 countsByYear W20563669692013 @default.
• W2056366969 crossrefType "journal-article" @default.
• W2056366969 hasAuthorship W2056366969A5027441298 @default.
• W2056366969 hasAuthorship W2056366969A5036774958 @default.
• W2056366969 hasAuthorship W2056366969A5053713371 @default.
• W2056366969 hasAuthorship W2056366969A5061259130 @default.
• W2056366969 hasAuthorship W2056366969A5069295773 @default.
• W2056366969 hasAuthorship W2056366969A5069878139 @default.
• W2056366969 hasAuthorship W2056366969A5091050205 @default.
• W2056366969 hasConcept C104317684 @default.
• W2056366969 hasConcept C134306372 @default.
• W2056366969 hasConcept C146587185 @default.
• W2056366969 hasConcept C159047783 @default.
• W2056366969 hasConcept C178790620 @default.
• W2056366969 hasConcept C185592680 @default.
• W2056366969 hasConcept C197336794 @default.
• W2056366969 hasConcept C2776620830 @default.
• W2056366969 hasConcept C2776983828 @default.
• W2056366969 hasConcept C2778458888 @default.
• W2056366969 hasConcept C2779583294 @default.
• W2056366969 hasConcept C2780454893 @default.
• W2056366969 hasConcept C2781253189 @default.
• W2056366969 hasConcept C33923547 @default.
• W2056366969 hasConcept C501593827 @default.
• W2056366969 hasConcept C523546767 @default.
• W2056366969 hasConcept C54355233 @default.
• W2056366969 hasConcept C544153396 @default.
• W2056366969 hasConcept C547475151 @default.
• W2056366969 hasConcept C55493867 @default.
• W2056366969 hasConcept C86803240 @default.
• W2056366969 hasConcept C89423630 @default.
• W2056366969 hasConceptScore W2056366969C104317684 @default.
• W2056366969 hasConceptScore W2056366969C134306372 @default.
• W2056366969 hasConceptScore W2056366969C146587185 @default.
• W2056366969 hasConceptScore W2056366969C159047783 @default.
• W2056366969 hasConceptScore W2056366969C178790620 @default.
• W2056366969 hasConceptScore W2056366969C185592680 @default.
• W2056366969 hasConceptScore W2056366969C197336794 @default.
• W2056366969 hasConceptScore W2056366969C2776620830 @default.
• W2056366969 hasConceptScore W2056366969C2776983828 @default.
• W2056366969 hasConceptScore W2056366969C2778458888 @default.
• W2056366969 hasConceptScore W2056366969C2779583294 @default.
• W2056366969 hasConceptScore W2056366969C2780454893 @default.
• W2056366969 hasConceptScore W2056366969C2781253189 @default.
• W2056366969 hasConceptScore W2056366969C33923547 @default.
• W2056366969 hasConceptScore W2056366969C501593827 @default.
• W2056366969 hasConceptScore W2056366969C523546767 @default.
• W2056366969 hasConceptScore W2056366969C54355233 @default.
• W2056366969 hasConceptScore W2056366969C544153396 @default.
• W2056366969 hasConceptScore W2056366969C547475151 @default.
• W2056366969 hasConceptScore W2056366969C55493867 @default.
• W2056366969 hasConceptScore W2056366969C86803240 @default.
• W2056366969 hasConceptScore W2056366969C89423630 @default.
• W2056366969 hasIssue "23-24" @default.
• W2056366969 hasLocation W20563669691 @default.
• W2056366969 hasLocation W20563669692 @default.
• W2056366969 hasOpenAccess W2056366969 @default.
• W2056366969 hasPrimaryLocation W20563669691 @default.
• W2056366969 hasRelatedWork W1987735630 @default.
• W2056366969 hasRelatedWork W2004664044 @default.
• W2056366969 hasRelatedWork W2056366969 @default.
• W2056366969 hasRelatedWork W2057888755 @default.
• W2056366969 hasRelatedWork W2108897235 @default.
• W2056366969 hasRelatedWork W2131238276 @default.

• next