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• W2056394265 abstract "We have analyzed the effect of CD3/T-cell receptor stimulation on GTP hydrolysis and GTP binding. We show that stimulation of Jurkat, T-cell, membranes withT3 results in a 50% increase in GTP hydrolysis which is specifically inhibited by GDP. Pretreatment of the membranes with neither pertussis toxin nor cholera toxin inhibited the GTP hydrolysis. We also show that stimulation withT3 increases the binding of GTPγS to Jurkat membranes. These data strongly implicate the involvement of a G-protein in CD3/T-cell receptor signalling." @default.
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• W2056394265 date "1989-07-03" @default.
• W2056394265 modified "2023-10-11" @default.
• W2056394265 title "CD3/T-cell receptor coupling to a pertussis and cholera toxin-insensitive G-protein" @default.
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• W2056394265 doi "https://doi.org/10.1016/0014-5793(89)80791-4" @default.
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