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- W2056414983 abstract "Stroke is a major cause of morbidity and mortality, and the application of evidence for stroke prevention varies considerably.To review the most recent, high-quality evidence for primary and secondary stroke prevention.Searches of MEDLINE, The Cochrane Library, and the ACP Journal Club were performed to identify English-language articles published from 1998 to 2001 that focused on primary and secondary stroke prevention. The references of each retrieved article were scanned, and experts in the field were contacted to identify additional relevant articles.Each of the articles was appraised, and its quality was graded with levels of evidence based on specific scientific methods that affect a study's validity.For primary prevention of stroke, adequate blood pressure reduction, and treatment of hyperlipidemia, use of antithrombotic therapy in patients with atrial fibrillation and of antiplatelet therapy in patients with myocardial infarction are effective and supported by evidence from several randomized trials. Effective strategies for the secondary prevention of stroke include treatment of hypertension and hyperlipidemia, antithrombotic therapy for patients with atrial fibrillation, antiplatelet therapy, and carotid endarterectomy in patients with severe carotid artery stenosis.Stroke is a major public health concern, and a significant body of evidence supports many primary and secondary prevention strategies." @default.
- W2056414983 created "2016-06-24" @default.
- W2056414983 creator A5007761401 @default.
- W2056414983 creator A5057812366 @default.
- W2056414983 creator A5067563008 @default.
- W2056414983 date "2002-09-18" @default.
- W2056414983 modified "2023-09-25" @default.
- W2056414983 title "New Evidence for Stroke Prevention" @default.
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- W2056414983 doi "https://doi.org/10.1001/jama.288.11.1388" @default.
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