Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056422076> ?p ?o ?g. }
- W2056422076 endingPage "720" @default.
- W2056422076 startingPage "715" @default.
- W2056422076 abstract "Endometrial cancer (EC) is the most common gynecologic malignancy of the female genital tract and the fourth most common neoplasia in women. In EC, myometrial invasion is considered one of the most important prognostic factors. For this process to occur, epithelial tumor cells need to undergo an epithelial to mesenchymal transition (EMT), either transiently or stably, and to differing degrees. This process has been extensively described in other types of cancer but has been poorly studied in EC. In this review, several features of EMT and the main molecular pathways responsible for triggering this process are investigated in relation to EC. The most common hallmarks of EMT have been found in EC, either at the level of E-cadherin loss or at the induction of its repressors, as well as other molecular alterations consistent with the mesenchymal phenotype-like L1CAM and BMI-1 up-regulation. Pathways including progesterone receptor, TGFβ, ETV5 and microRNAs are deeply related to the EMT process in EC." @default.
- W2056422076 created "2016-06-24" @default.
- W2056422076 creator A5008381818 @default.
- W2056422076 creator A5008533017 @default.
- W2056422076 creator A5009695720 @default.
- W2056422076 creator A5011383516 @default.
- W2056422076 creator A5012466556 @default.
- W2056422076 creator A5024002938 @default.
- W2056422076 creator A5025681066 @default.
- W2056422076 creator A5027132310 @default.
- W2056422076 creator A5037023029 @default.
- W2056422076 creator A5037049238 @default.
- W2056422076 creator A5040711804 @default.
- W2056422076 creator A5042199240 @default.
- W2056422076 creator A5043227623 @default.
- W2056422076 creator A5045282403 @default.
- W2056422076 creator A5047957100 @default.
- W2056422076 creator A5048840478 @default.
- W2056422076 creator A5049702399 @default.
- W2056422076 creator A5058485099 @default.
- W2056422076 creator A5068868892 @default.
- W2056422076 creator A5069925431 @default.
- W2056422076 creator A5080033429 @default.
- W2056422076 creator A5084944686 @default.
- W2056422076 creator A5086724321 @default.
- W2056422076 creator A5090159813 @default.
- W2056422076 creator A5091776890 @default.
- W2056422076 date "2012-08-22" @default.
- W2056422076 modified "2023-10-16" @default.
- W2056422076 title "The EMT signaling pathways in endometrial carcinoma" @default.
- W2056422076 cites W144423133 @default.
- W2056422076 cites W1525502277 @default.
- W2056422076 cites W1933506009 @default.
- W2056422076 cites W1971303929 @default.
- W2056422076 cites W1972175293 @default.
- W2056422076 cites W1976614888 @default.
- W2056422076 cites W1979443145 @default.
- W2056422076 cites W1986578434 @default.
- W2056422076 cites W1987473368 @default.
- W2056422076 cites W1996350041 @default.
- W2056422076 cites W1997694169 @default.
- W2056422076 cites W2007331689 @default.
- W2056422076 cites W2007956592 @default.
- W2056422076 cites W2008164658 @default.
- W2056422076 cites W2010831408 @default.
- W2056422076 cites W2012124753 @default.
- W2056422076 cites W2013336475 @default.
- W2056422076 cites W2019294425 @default.
- W2056422076 cites W2021605685 @default.
- W2056422076 cites W2022456153 @default.
- W2056422076 cites W2022557585 @default.
- W2056422076 cites W2031036488 @default.
- W2056422076 cites W2035653659 @default.
- W2056422076 cites W2039343577 @default.
- W2056422076 cites W2039986126 @default.
- W2056422076 cites W2044869180 @default.
- W2056422076 cites W2047553717 @default.
- W2056422076 cites W2058667985 @default.
- W2056422076 cites W2059871392 @default.
- W2056422076 cites W2063011414 @default.
- W2056422076 cites W2063288598 @default.
- W2056422076 cites W2070058781 @default.
- W2056422076 cites W2076188603 @default.
- W2056422076 cites W2078502914 @default.
- W2056422076 cites W2084057317 @default.
- W2056422076 cites W2089199921 @default.
- W2056422076 cites W2089880928 @default.
- W2056422076 cites W2110935705 @default.
- W2056422076 cites W2117692326 @default.
- W2056422076 cites W2124022855 @default.
- W2056422076 cites W2125195199 @default.
- W2056422076 cites W2125713917 @default.
- W2056422076 cites W2131545912 @default.
- W2056422076 cites W2134203671 @default.
- W2056422076 cites W2136280424 @default.
- W2056422076 cites W2139409822 @default.
- W2056422076 cites W2140551998 @default.
- W2056422076 cites W2143077170 @default.
- W2056422076 cites W2144545651 @default.
- W2056422076 cites W2144953052 @default.
- W2056422076 cites W2148929244 @default.
- W2056422076 cites W2149504763 @default.
- W2056422076 cites W2156583045 @default.
- W2056422076 cites W2159381160 @default.
- W2056422076 cites W2160246022 @default.
- W2056422076 cites W2160459271 @default.
- W2056422076 cites W2162550420 @default.
- W2056422076 cites W2165948908 @default.
- W2056422076 cites W2166666333 @default.
- W2056422076 cites W2170035372 @default.
- W2056422076 cites W2170608612 @default.
- W2056422076 cites W2171296186 @default.
- W2056422076 cites W4211047904 @default.
- W2056422076 doi "https://doi.org/10.1007/s12094-012-0866-3" @default.
- W2056422076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22911547" @default.
- W2056422076 hasPublicationYear "2012" @default.
- W2056422076 type Work @default.
- W2056422076 sameAs 2056422076 @default.