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- W2056465433 abstract "Incretin hormones, namely glucagon-like peptide 1 (GLP-1) and gastric inhibitory peptide, have been recognized for some time as playing a key role in glucose homeostasis, with the effects of incretin hormones believed to be responsible for up to 60% of postprandial insulin release. Two predominant therapeutic strategies have been developed to augment the incretin response: (1) GLP-1 receptor agonists resistant to degradation by the enzyme dipeptidyl peptidase 4 (DPP-4); and (2) DPP-4 inhibitors. With an expanding arsenal of incretin-based therapies available, understanding the differentiating efficacy and safety profiles for available agents is important in optimizing drug selection and patient outcomes." @default.
- W2056465433 created "2016-06-24" @default.
- W2056465433 creator A5082350484 @default.
- W2056465433 date "2015-01-01" @default.
- W2056465433 modified "2023-10-11" @default.
- W2056465433 title "Incretin-Based Therapies" @default.
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- W2056465433 doi "https://doi.org/10.1016/j.mcna.2014.08.013" @default.
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