Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056480129> ?p ?o ?g. }
- W2056480129 endingPage "595" @default.
- W2056480129 startingPage "586" @default.
- W2056480129 abstract "The presence of antineutrophil cytoplasmic autoantibodies with specificity for proteinase 3 (PR3-ANCA) usually is detected by enzyme-linked immunosorbent assay (ELISA) with purified PR3 as a substrate. We studied the technical performance of direct and capture ELISA using a recombinant proteolytically inactive form of PR3 produced in the baculovirus expression system for the detection of PR3-ANCA in 114 patients with systemic vasculitis at diagnosis. We found that ELISA using recombinant PR3 produced in insect cells is a promising alternative for ELISA with native PR3. We found a correlation between tests using recombinant or native PR3, as well as correlation of the ELISA results with ANCA titers measured by the indirect immunofluorescence technique. However, the specificity for ANCA-associated vasculitis of ELISA with recombinant PR3 was lower than ELISA using native PR3. Compared with the direct assay, capture ELISA is a more sensitive method for PR3-ANCA detection, with both native and recombinant PR3, and its results depend on the monoclonal antibody used to capture the antigen." @default.
- W2056480129 created "2016-06-24" @default.
- W2056480129 creator A5005053030 @default.
- W2056480129 creator A5008889473 @default.
- W2056480129 creator A5032246543 @default.
- W2056480129 creator A5037942433 @default.
- W2056480129 creator A5051953810 @default.
- W2056480129 creator A5066701459 @default.
- W2056480129 creator A5071443955 @default.
- W2056480129 creator A5080943664 @default.
- W2056480129 creator A5088080631 @default.
- W2056480129 date "2003-10-01" @default.
- W2056480129 modified "2023-09-27" @default.
- W2056480129 title "Recombinant Protein to Analyze Autoantibodies to Proteinase 3 in Systemic Vasculitis" @default.
- W2056480129 cites W1510755189 @default.
- W2056480129 cites W1605823388 @default.
- W2056480129 cites W1973784016 @default.
- W2056480129 cites W1975628624 @default.
- W2056480129 cites W1979989219 @default.
- W2056480129 cites W1981612604 @default.
- W2056480129 cites W1990119153 @default.
- W2056480129 cites W1990486811 @default.
- W2056480129 cites W2015359612 @default.
- W2056480129 cites W2027807255 @default.
- W2056480129 cites W2030446630 @default.
- W2056480129 cites W2031866992 @default.
- W2056480129 cites W2037239628 @default.
- W2056480129 cites W2037825857 @default.
- W2056480129 cites W2039582264 @default.
- W2056480129 cites W2044732270 @default.
- W2056480129 cites W2047619454 @default.
- W2056480129 cites W2051213302 @default.
- W2056480129 cites W2052334080 @default.
- W2056480129 cites W2078246124 @default.
- W2056480129 cites W2083446756 @default.
- W2056480129 cites W2083777349 @default.
- W2056480129 cites W2100459433 @default.
- W2056480129 cites W2103874411 @default.
- W2056480129 cites W2114302525 @default.
- W2056480129 cites W2123092609 @default.
- W2056480129 cites W2125910117 @default.
- W2056480129 cites W2141860644 @default.
- W2056480129 cites W2144966307 @default.
- W2056480129 cites W2146203649 @default.
- W2056480129 cites W2150612435 @default.
- W2056480129 cites W2162725007 @default.
- W2056480129 cites W2170705556 @default.
- W2056480129 cites W2170737062 @default.
- W2056480129 cites W2264075806 @default.
- W2056480129 cites W2317186316 @default.
- W2056480129 cites W2332954012 @default.
- W2056480129 cites W2415558687 @default.
- W2056480129 cites W2435997465 @default.
- W2056480129 cites W69784438 @default.
- W2056480129 cites W2416113114 @default.
- W2056480129 doi "https://doi.org/10.1309/ytu2fuhbexjlwmld" @default.
- W2056480129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14560570" @default.
- W2056480129 hasPublicationYear "2003" @default.
- W2056480129 type Work @default.
- W2056480129 sameAs 2056480129 @default.
- W2056480129 citedByCount "9" @default.
- W2056480129 countsByYear W20564801292013 @default.
- W2056480129 crossrefType "journal-article" @default.
- W2056480129 hasAuthorship W2056480129A5005053030 @default.
- W2056480129 hasAuthorship W2056480129A5008889473 @default.
- W2056480129 hasAuthorship W2056480129A5032246543 @default.
- W2056480129 hasAuthorship W2056480129A5037942433 @default.
- W2056480129 hasAuthorship W2056480129A5051953810 @default.
- W2056480129 hasAuthorship W2056480129A5066701459 @default.
- W2056480129 hasAuthorship W2056480129A5071443955 @default.
- W2056480129 hasAuthorship W2056480129A5080943664 @default.
- W2056480129 hasAuthorship W2056480129A5088080631 @default.
- W2056480129 hasBestOaLocation W20564801291 @default.
- W2056480129 hasConcept C104317684 @default.
- W2056480129 hasConcept C142724271 @default.
- W2056480129 hasConcept C159654299 @default.
- W2056480129 hasConcept C163764329 @default.
- W2056480129 hasConcept C203014093 @default.
- W2056480129 hasConcept C21194631 @default.
- W2056480129 hasConcept C2776015282 @default.
- W2056480129 hasConcept C2777374719 @default.
- W2056480129 hasConcept C2779134260 @default.
- W2056480129 hasConcept C40767141 @default.
- W2056480129 hasConcept C55493867 @default.
- W2056480129 hasConcept C71924100 @default.
- W2056480129 hasConcept C86803240 @default.
- W2056480129 hasConceptScore W2056480129C104317684 @default.
- W2056480129 hasConceptScore W2056480129C142724271 @default.
- W2056480129 hasConceptScore W2056480129C159654299 @default.
- W2056480129 hasConceptScore W2056480129C163764329 @default.
- W2056480129 hasConceptScore W2056480129C203014093 @default.
- W2056480129 hasConceptScore W2056480129C21194631 @default.
- W2056480129 hasConceptScore W2056480129C2776015282 @default.
- W2056480129 hasConceptScore W2056480129C2777374719 @default.
- W2056480129 hasConceptScore W2056480129C2779134260 @default.
- W2056480129 hasConceptScore W2056480129C40767141 @default.
- W2056480129 hasConceptScore W2056480129C55493867 @default.
- W2056480129 hasConceptScore W2056480129C71924100 @default.