Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056491567> ?p ?o ?g. }
- W2056491567 endingPage "776" @default.
- W2056491567 startingPage "771" @default.
- W2056491567 abstract "MicroRNAs (miRNAs) are small RNAs that do not code for proteins, but function by controlling protein expression of other genes. miRNAs have been shown to control cell growth, differentiation and apoptosis. Shortly after their discovery, miRNAs have been found to be associated with cancer. Earlier reports have shown that human cancers frequently show a distorted expression profile of miRNAs. In this review, the biogenesis of miRNAs and potential mechanisms of their dysregulation and involvement in cancer pathogenesis are discussed. The current literature on potential applications of miRNAs in the field of clinical oncology from diagnostic to prognostic and predictive applications at the tissue, and more recently, serum levels, is reviewed. The potential therapeutic applications of miRNAs and RNAi in the field of cancer are summarised. Finally, some of the potential challenges that face the transition of miRNAs from a research setting into a clinical application are highlighted, with a future prospective of the incorporation of miRNAs in cancer patient management." @default.
- W2056491567 created "2016-06-24" @default.
- W2056491567 creator A5038476466 @default.
- W2056491567 creator A5050764803 @default.
- W2056491567 creator A5085603937 @default.
- W2056491567 date "2009-09-01" @default.
- W2056491567 modified "2023-10-18" @default.
- W2056491567 title "MicroRNAs in clinical oncology: at the crossroads between promises and problems" @default.
- W2056491567 cites W144423133 @default.
- W2056491567 cites W1601459316 @default.
- W2056491567 cites W1967610681 @default.
- W2056491567 cites W1975304818 @default.
- W2056491567 cites W1975647849 @default.
- W2056491567 cites W1985517310 @default.
- W2056491567 cites W1990645475 @default.
- W2056491567 cites W2001527245 @default.
- W2056491567 cites W2001616285 @default.
- W2056491567 cites W2006797972 @default.
- W2056491567 cites W2007103799 @default.
- W2056491567 cites W2010622876 @default.
- W2056491567 cites W2014946489 @default.
- W2056491567 cites W2019742102 @default.
- W2056491567 cites W2023858596 @default.
- W2056491567 cites W2024825778 @default.
- W2056491567 cites W2026570544 @default.
- W2056491567 cites W2036224487 @default.
- W2056491567 cites W2036404063 @default.
- W2056491567 cites W2036774788 @default.
- W2056491567 cites W2038167014 @default.
- W2056491567 cites W2038696333 @default.
- W2056491567 cites W2045228008 @default.
- W2056491567 cites W2045347539 @default.
- W2056491567 cites W2047455573 @default.
- W2056491567 cites W2047529648 @default.
- W2056491567 cites W2047754201 @default.
- W2056491567 cites W2055611241 @default.
- W2056491567 cites W2056850160 @default.
- W2056491567 cites W2062823747 @default.
- W2056491567 cites W2066592277 @default.
- W2056491567 cites W2070470683 @default.
- W2056491567 cites W2070571588 @default.
- W2056491567 cites W2075329854 @default.
- W2056491567 cites W2078355129 @default.
- W2056491567 cites W2078684282 @default.
- W2056491567 cites W2079251691 @default.
- W2056491567 cites W2079372953 @default.
- W2056491567 cites W2080240500 @default.
- W2056491567 cites W2081119041 @default.
- W2056491567 cites W2084169171 @default.
- W2056491567 cites W2084400739 @default.
- W2056491567 cites W2087339923 @default.
- W2056491567 cites W2088555384 @default.
- W2056491567 cites W2091386059 @default.
- W2056491567 cites W2095229706 @default.
- W2056491567 cites W2097233439 @default.
- W2056491567 cites W2100084607 @default.
- W2056491567 cites W2104905829 @default.
- W2056491567 cites W2108402531 @default.
- W2056491567 cites W2113209482 @default.
- W2056491567 cites W2115093090 @default.
- W2056491567 cites W2116302563 @default.
- W2056491567 cites W2117391818 @default.
- W2056491567 cites W2123079914 @default.
- W2056491567 cites W2127207254 @default.
- W2056491567 cites W2130979840 @default.
- W2056491567 cites W2131883344 @default.
- W2056491567 cites W2135314242 @default.
- W2056491567 cites W2135810600 @default.
- W2056491567 cites W2135836598 @default.
- W2056491567 cites W2138664009 @default.
- W2056491567 cites W2142221925 @default.
- W2056491567 cites W2144372599 @default.
- W2056491567 cites W2150696691 @default.
- W2056491567 cites W2154551754 @default.
- W2056491567 cites W2155123146 @default.
- W2056491567 cites W2156132739 @default.
- W2056491567 cites W2160905065 @default.
- W2056491567 cites W2162425895 @default.
- W2056491567 cites W2163482204 @default.
- W2056491567 cites W2419363702 @default.
- W2056491567 cites W2481323403 @default.
- W2056491567 cites W2489091007 @default.
- W2056491567 doi "https://doi.org/10.1136/jcp.2009.064717" @default.
- W2056491567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19734473" @default.
- W2056491567 hasPublicationYear "2009" @default.
- W2056491567 type Work @default.
- W2056491567 sameAs 2056491567 @default.
- W2056491567 citedByCount "74" @default.
- W2056491567 countsByYear W20564915672012 @default.
- W2056491567 countsByYear W20564915672013 @default.
- W2056491567 countsByYear W20564915672014 @default.
- W2056491567 countsByYear W20564915672015 @default.
- W2056491567 countsByYear W20564915672016 @default.
- W2056491567 countsByYear W20564915672017 @default.
- W2056491567 countsByYear W20564915672019 @default.
- W2056491567 countsByYear W20564915672020 @default.
- W2056491567 countsByYear W20564915672021 @default.
- W2056491567 countsByYear W20564915672022 @default.