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- W2056511887 abstract "The factors that lead to high-affinity binding are a good fit between the surfaces of the two molecules in their ground state and charge complementarity. Exactly the same factors give high specificity for a target. We argue that selection for high-affinity binding automatically leads to highly specific binding. This principle can be used to simplify screening approaches aimed at generating useful drugs." @default.
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- W2056511887 date "1995-10-01" @default.
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- W2056511887 title "Let's get specific: the relationship between specificity and affinity" @default.
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- W2056511887 doi "https://doi.org/10.1016/1074-5521(95)90023-3" @default.
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