FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056516685> ?p ?o ?g. }

• W2056516685 endingPage "670" @default.
• W2056516685 startingPage "662" @default.
• W2056516685 abstract "Many animal models of alcoholism have targeted aspects of excessive alcohol intake (abuse) and dependence. In the rodent, models aimed at increasing alcohol self-administration have used genetic or environmental manipulations, or their combination. Strictly genetic manipulations (e.g., comparison of inbred strains or targeted mutants, selective breeding) have not yielded rat or mouse genotypes that will regularly and voluntarily drink alcohol to the point of intoxication. Although some behavioral manipulations (e.g., scheduling or limiting access to alcohol, adding a sweetener) will induce mice or rats to drink enough alcohol to become intoxicated, these typically require significant food or water restriction or a long time to develop. We report progress toward the development of a new genetic animal model for high levels of alcohol drinking.High Drinking in the Dark (HDID-1) mice have been selectively bred for high blood ethanol concentrations (BEC, ideally exceeding 100 mg%) resulting from the ingestion of a 20% alcohol solution.After 11 generations of selection, more than 56% of the population now exceeds this BEC after a 4-hour drinking session in which a single bottle containing 20% ethanol is available. The dose of ethanol consumed also produced quantifiable signs of intoxication.These mice will be useful for mechanistic studies of the biological and genetic contributions to excessive drinking." @default.
• W2056516685 created "2016-06-24" @default.
• W2056516685 creator A5008609077 @default.
• W2056516685 creator A5028340956 @default.
• W2056516685 creator A5038492593 @default.
• W2056516685 creator A5041043150 @default.
• W2056516685 creator A5053942773 @default.
• W2056516685 creator A5080938029 @default.
• W2056516685 creator A5084447586 @default.
• W2056516685 date "2009-04-01" @default.
• W2056516685 modified "2023-10-14" @default.
• W2056516685 title "A Line of Mice Selected for High Blood Ethanol Concentrations Shows Drinking in the Dark to Intoxication" @default.
• W2056516685 cites W1970885792 @default.
• W2056516685 cites W1975875405 @default.
• W2056516685 cites W1977498657 @default.
• W2056516685 cites W1978008209 @default.
• W2056516685 cites W1987316565 @default.
• W2056516685 cites W1997278612 @default.
• W2056516685 cites W2019101826 @default.
• W2056516685 cites W2021489067 @default.
• W2056516685 cites W2026559287 @default.
• W2056516685 cites W2028858200 @default.
• W2056516685 cites W2036751844 @default.
• W2056516685 cites W2041172290 @default.
• W2056516685 cites W2042631675 @default.
• W2056516685 cites W2046649514 @default.
• W2056516685 cites W2047486552 @default.
• W2056516685 cites W2057104160 @default.
• W2056516685 cites W2057977335 @default.
• W2056516685 cites W2064323618 @default.
• W2056516685 cites W2067038697 @default.
• W2056516685 cites W2079214445 @default.
• W2056516685 cites W2081336349 @default.
• W2056516685 cites W2082328553 @default.
• W2056516685 cites W2108384113 @default.
• W2056516685 cites W2141499043 @default.
• W2056516685 cites W2145081020 @default.
• W2056516685 cites W2153435327 @default.
• W2056516685 cites W2157759655 @default.
• W2056516685 cites W2158162458 @default.
• W2056516685 cites W3019801591 @default.
• W2056516685 doi "https://doi.org/10.1016/j.biopsych.2008.11.002" @default.
• W2056516685 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3330756" @default.
• W2056516685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19095222" @default.
• W2056516685 hasPublicationYear "2009" @default.
• W2056516685 type Work @default.
• W2056516685 sameAs 2056516685 @default.
• W2056516685 citedByCount "139" @default.
• W2056516685 countsByYear W20565166852012 @default.
• W2056516685 countsByYear W20565166852013 @default.
• W2056516685 countsByYear W20565166852014 @default.
• W2056516685 countsByYear W20565166852015 @default.
• W2056516685 countsByYear W20565166852016 @default.
• W2056516685 countsByYear W20565166852017 @default.
• W2056516685 countsByYear W20565166852018 @default.
• W2056516685 countsByYear W20565166852019 @default.
• W2056516685 countsByYear W20565166852020 @default.
• W2056516685 countsByYear W20565166852021 @default.
• W2056516685 countsByYear W20565166852022 @default.
• W2056516685 countsByYear W20565166852023 @default.
• W2056516685 crossrefType "journal-article" @default.
• W2056516685 hasAuthorship W2056516685A5008609077 @default.
• W2056516685 hasAuthorship W2056516685A5028340956 @default.
• W2056516685 hasAuthorship W2056516685A5038492593 @default.
• W2056516685 hasAuthorship W2056516685A5041043150 @default.
• W2056516685 hasAuthorship W2056516685A5053942773 @default.
• W2056516685 hasAuthorship W2056516685A5080938029 @default.
• W2056516685 hasAuthorship W2056516685A5084447586 @default.
• W2056516685 hasBestOaLocation W20565166852 @default.
• W2056516685 hasConcept C118552586 @default.
• W2056516685 hasConcept C12558332 @default.
• W2056516685 hasConcept C126322002 @default.
• W2056516685 hasConcept C193230392 @default.
• W2056516685 hasConcept C2778117688 @default.
• W2056516685 hasConcept C2780161600 @default.
• W2056516685 hasConcept C2780931562 @default.
• W2056516685 hasConcept C2781066024 @default.
• W2056516685 hasConcept C2908647359 @default.
• W2056516685 hasConcept C33070731 @default.
• W2056516685 hasConcept C42407357 @default.
• W2056516685 hasConcept C54355233 @default.
• W2056516685 hasConcept C55493867 @default.
• W2056516685 hasConcept C71924100 @default.
• W2056516685 hasConcept C86803240 @default.
• W2056516685 hasConcept C99454951 @default.
• W2056516685 hasConceptScore W2056516685C118552586 @default.
• W2056516685 hasConceptScore W2056516685C12558332 @default.
• W2056516685 hasConceptScore W2056516685C126322002 @default.
• W2056516685 hasConceptScore W2056516685C193230392 @default.
• W2056516685 hasConceptScore W2056516685C2778117688 @default.
• W2056516685 hasConceptScore W2056516685C2780161600 @default.
• W2056516685 hasConceptScore W2056516685C2780931562 @default.
• W2056516685 hasConceptScore W2056516685C2781066024 @default.
• W2056516685 hasConceptScore W2056516685C2908647359 @default.
• W2056516685 hasConceptScore W2056516685C33070731 @default.
• W2056516685 hasConceptScore W2056516685C42407357 @default.
• W2056516685 hasConceptScore W2056516685C54355233 @default.
• W2056516685 hasConceptScore W2056516685C55493867 @default.

• next