FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056519542> ?p ?o ?g. }

• W2056519542 abstract "Certain tumour cells contain activated ras genes that code for 21 000 dalton proteins (p21). These proteins associate with the inner face of the plasma membrane and bind guanine nucleotides specifically. In order to determine whether p21s have functions similar to other GTP binding proteins, we investigated the regulation, by guanine nucleotides, of adenylate cyclase (AC) activity in membrane preparations isolated from fibroblasts (C127) transformed by a temperature sensitive mutant of Kirsten sarcoma virus (Ts 371). The degree of AC stimulation by GMP P(NH)P increased when these cells were shifted from the permissive temperature (33 degrees C) to the non-permissive temperature (39 degrees C). This effect was more pronounced at low Mg++ and low GMP P(NH)P concentrations. AC stimulation remained unchanged in rat fibroblasts infected with a temperature sensitive mutant of Rous Sarcoma virus. AC activity was depressed in C127 cells infected with wild type KiMSV. Our data illustrate the feasibility of correlating alterations in the AC system with ras gene expression and using such experimental approaches to elucidate the physiological functions of the p21 proteins." @default.
• W2056519542 created "2016-06-24" @default.
• W2056519542 creator A5025824876 @default.
• W2056519542 creator A5043847041 @default.
• W2056519542 creator A5059199395 @default.
• W2056519542 date "1985-02-01" @default.
• W2056519542 modified "2023-10-06" @default.
• W2056519542 title "Modulation of adenylate cyclase by guanine nucleotides and kirsten sarcoma virus mediated transformation" @default.
• W2056519542 cites W1484483886 @default.
• W2056519542 cites W1535668052 @default.
• W2056519542 cites W1569033208 @default.
• W2056519542 cites W1775749144 @default.
• W2056519542 cites W1940081151 @default.
• W2056519542 cites W1967452306 @default.
• W2056519542 cites W1968050307 @default.
• W2056519542 cites W1982150099 @default.
• W2056519542 cites W1992444908 @default.
• W2056519542 cites W1995723368 @default.
• W2056519542 cites W1996729627 @default.
• W2056519542 cites W2001006416 @default.
• W2056519542 cites W2001923549 @default.
• W2056519542 cites W2013973825 @default.
• W2056519542 cites W2014003943 @default.
• W2056519542 cites W2014798701 @default.
• W2056519542 cites W2017362824 @default.
• W2056519542 cites W2024068070 @default.
• W2056519542 cites W2028519621 @default.
• W2056519542 cites W2058531019 @default.
• W2056519542 cites W2058649415 @default.
• W2056519542 cites W2068817943 @default.
• W2056519542 cites W2085093642 @default.
• W2056519542 cites W2095018874 @default.
• W2056519542 cites W2113210366 @default.
• W2056519542 cites W2165446716 @default.
• W2056519542 cites W2178536469 @default.
• W2056519542 cites W2317659315 @default.
• W2056519542 cites W301540371 @default.
• W2056519542 cites W84361437 @default.
• W2056519542 doi "https://doi.org/10.1016/s0006-291x(85)80161-3" @default.
• W2056519542 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2983713" @default.
• W2056519542 hasPublicationYear "1985" @default.
• W2056519542 type Work @default.
• W2056519542 sameAs 2056519542 @default.
• W2056519542 citedByCount "34" @default.
• W2056519542 countsByYear W20565195422012 @default.
• W2056519542 countsByYear W20565195422013 @default.
• W2056519542 countsByYear W20565195422016 @default.
• W2056519542 countsByYear W20565195422018 @default.
• W2056519542 crossrefType "journal-article" @default.
• W2056519542 hasAuthorship W2056519542A5025824876 @default.
• W2056519542 hasAuthorship W2056519542A5043847041 @default.
• W2056519542 hasAuthorship W2056519542A5059199395 @default.
• W2056519542 hasConcept C104317684 @default.
• W2056519542 hasConcept C118716 @default.
• W2056519542 hasConcept C134018914 @default.
• W2056519542 hasConcept C143065580 @default.
• W2056519542 hasConcept C153911025 @default.
• W2056519542 hasConcept C159047783 @default.
• W2056519542 hasConcept C170493617 @default.
• W2056519542 hasConcept C180526460 @default.
• W2056519542 hasConcept C181199279 @default.
• W2056519542 hasConcept C185592680 @default.
• W2056519542 hasConcept C24998067 @default.
• W2056519542 hasConcept C2522874641 @default.
• W2056519542 hasConcept C2776638253 @default.
• W2056519542 hasConcept C2777441520 @default.
• W2056519542 hasConcept C2778301229 @default.
• W2056519542 hasConcept C2780069284 @default.
• W2056519542 hasConcept C512185932 @default.
• W2056519542 hasConcept C55493867 @default.
• W2056519542 hasConcept C86803240 @default.
• W2056519542 hasConcept C95444343 @default.
• W2056519542 hasConceptScore W2056519542C104317684 @default.
• W2056519542 hasConceptScore W2056519542C118716 @default.
• W2056519542 hasConceptScore W2056519542C134018914 @default.
• W2056519542 hasConceptScore W2056519542C143065580 @default.
• W2056519542 hasConceptScore W2056519542C153911025 @default.
• W2056519542 hasConceptScore W2056519542C159047783 @default.
• W2056519542 hasConceptScore W2056519542C170493617 @default.
• W2056519542 hasConceptScore W2056519542C180526460 @default.
• W2056519542 hasConceptScore W2056519542C181199279 @default.
• W2056519542 hasConceptScore W2056519542C185592680 @default.
• W2056519542 hasConceptScore W2056519542C24998067 @default.
• W2056519542 hasConceptScore W2056519542C2522874641 @default.
• W2056519542 hasConceptScore W2056519542C2776638253 @default.
• W2056519542 hasConceptScore W2056519542C2777441520 @default.
• W2056519542 hasConceptScore W2056519542C2778301229 @default.
• W2056519542 hasConceptScore W2056519542C2780069284 @default.
• W2056519542 hasConceptScore W2056519542C512185932 @default.
• W2056519542 hasConceptScore W2056519542C55493867 @default.
• W2056519542 hasConceptScore W2056519542C86803240 @default.
• W2056519542 hasConceptScore W2056519542C95444343 @default.
• W2056519542 hasLocation W20565195421 @default.
• W2056519542 hasLocation W20565195422 @default.
• W2056519542 hasOpenAccess W2056519542 @default.
• W2056519542 hasPrimaryLocation W20565195421 @default.
• W2056519542 hasRelatedWork W148461917 @default.
• W2056519542 hasRelatedWork W1510838637 @default.
• W2056519542 hasRelatedWork W1677760409 @default.
• W2056519542 hasRelatedWork W1995294014 @default.

• next