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- W2056521217 abstract "Hairy cell leukemia is a rare, indolent, chronic lymphoproliferative disorder characterized by the proliferation of a malignant B-cell clone with irregular cytoplasmic projections. Treatment with purine analogs such as 2-chlorodeoxyadenosine (2-CdA) is associated with excellent remission rates and long-term survival. Although the majority of patients achieve a complete remission (CR), most have minimal residual disease detected by sensitive methods. Despite the long term disease-free survival, approximately 36% of patients relapse and many require further therapy. Repeat administration of 2-CdA is very effective in achieving a second CR. Recently, new agents such rituximab and BL22 were shown to be effective in the treatment of relapsed and refractory disease." @default.
- W2056521217 created "2016-06-24" @default.
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- W2056521217 date "2006-01-01" @default.
- W2056521217 modified "2023-09-25" @default.
- W2056521217 title "2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up" @default.
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- W2056521217 doi "https://doi.org/10.1080/10428190600822052" @default.
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