FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2056522147> ?p ?o ?g. }

• W2056522147 endingPage "57" @default.
• W2056522147 startingPage "49" @default.
• W2056522147 abstract "Numerous clinical studies link cytomegalovirus (CMV) infection with incomplete posttransplantation T-cell recovery. We hypothesized that the inability of transplant recipients to handle CMV reactivation might correlate with a defective graft-versus-leukemia response and increased posttransplantation morbidity. Between May 1995 and August 2001, 82 patients who were CMV seropositive and survived the first 100 days after transplantation were identified for a day 100 landmark analysis of the effect of CMV reactivation patterns on eventual transplantation outcome. All patients underwent a myeloablative HLA-identical sibling donor T cell-depleted stem cell transplantation with scheduled donor T-cell add-back on day 45. Median follow-up was 1032 days. Forty-two patients who had either no reactivation or only 1 positive test with quick clearance were designated as a CMV immune competent group. Forty patients designated as CMV immune deficient (ID) had at least 2 positive tests. Apart from younger age (33 versus 38 years; P =.05) in the ID group, the 2 groups were balanced for clinical characteristics. In multivariate analysis, ID patients had a significantly higher incidence of leukemia relapse (58% versus 21%; P =.03) and worse disease-free survival (31% versus 66%; P =.04). There was no significant difference in week 1 to 14 posttransplantation lymphocyte counts between the 2 groups. In 67 patients tested 3 to 6 months after transplantation, a proliferative response to CMV antigen (stimulation index > or =2) occurred in 27 of 36 immune competent patients compared with 15 of 31 ID patients (P =.006). These results show that recurrent CMV reactivation in the first 100 days after transplantation predicts for reduced disease-free survival and increased leukemic relapse beyond 100 days and correlates with inferior proliferative responses to CMV. The higher relapse rate may reflect poor immune reconstitution in ID patients or an adverse effect of prolonged antiviral treatment." @default.
• W2056522147 created "2016-06-24" @default.
• W2056522147 creator A5006999192 @default.
• W2056522147 creator A5049066393 @default.
• W2056522147 creator A5051945309 @default.
• W2056522147 creator A5052340930 @default.
• W2056522147 creator A5056611428 @default.
• W2056522147 creator A5062772036 @default.
• W2056522147 creator A5074515375 @default.
• W2056522147 creator A5078997248 @default.
• W2056522147 creator A5086494836 @default.
• W2056522147 date "2004-01-01" @default.
• W2056522147 modified "2023-10-09" @default.
• W2056522147 title "Persisting posttransplantation cytomegalovirus antigenemia correlates with poor lymphocyte proliferation to cytomegalovirus antigen and predicts for increased late relapse and treatment failure" @default.
• W2056522147 cites W144116704 @default.
• W2056522147 cites W1568041502 @default.
• W2056522147 cites W1968618136 @default.
• W2056522147 cites W1982044703 @default.
• W2056522147 cites W1990361684 @default.
• W2056522147 cites W1992577488 @default.
• W2056522147 cites W2003979549 @default.
• W2056522147 cites W2013235252 @default.
• W2056522147 cites W2015828912 @default.
• W2056522147 cites W2048527095 @default.
• W2056522147 cites W2062414473 @default.
• W2056522147 cites W2067475735 @default.
• W2056522147 cites W2073493139 @default.
• W2056522147 cites W2076257803 @default.
• W2056522147 cites W2076919967 @default.
• W2056522147 cites W2091704657 @default.
• W2056522147 cites W2108238886 @default.
• W2056522147 cites W2111653667 @default.
• W2056522147 cites W2113603236 @default.
• W2056522147 cites W2136013587 @default.
• W2056522147 cites W2142234156 @default.
• W2056522147 cites W2219670565 @default.
• W2056522147 cites W2229306814 @default.
• W2056522147 cites W2263584158 @default.
• W2056522147 cites W2334218438 @default.
• W2056522147 cites W40694895 @default.
• W2056522147 cites W4243292895 @default.
• W2056522147 cites W4293241248 @default.
• W2056522147 cites W5387557 @default.
• W2056522147 doi "https://doi.org/10.1016/j.bbmt.2003.08.011" @default.
• W2056522147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14752779" @default.
• W2056522147 hasPublicationYear "2004" @default.
• W2056522147 type Work @default.
• W2056522147 sameAs 2056522147 @default.
• W2056522147 citedByCount "60" @default.
• W2056522147 countsByYear W20565221472012 @default.
• W2056522147 countsByYear W20565221472013 @default.
• W2056522147 countsByYear W20565221472014 @default.
• W2056522147 countsByYear W20565221472015 @default.
• W2056522147 countsByYear W20565221472016 @default.
• W2056522147 countsByYear W20565221472017 @default.
• W2056522147 countsByYear W20565221472018 @default.
• W2056522147 countsByYear W20565221472019 @default.
• W2056522147 countsByYear W20565221472020 @default.
• W2056522147 countsByYear W20565221472021 @default.
• W2056522147 countsByYear W20565221472022 @default.
• W2056522147 countsByYear W20565221472023 @default.
• W2056522147 crossrefType "journal-article" @default.
• W2056522147 hasAuthorship W2056522147A5006999192 @default.
• W2056522147 hasAuthorship W2056522147A5049066393 @default.
• W2056522147 hasAuthorship W2056522147A5051945309 @default.
• W2056522147 hasAuthorship W2056522147A5052340930 @default.
• W2056522147 hasAuthorship W2056522147A5056611428 @default.
• W2056522147 hasAuthorship W2056522147A5062772036 @default.
• W2056522147 hasAuthorship W2056522147A5074515375 @default.
• W2056522147 hasAuthorship W2056522147A5078997248 @default.
• W2056522147 hasAuthorship W2056522147A5086494836 @default.
• W2056522147 hasBestOaLocation W20565221471 @default.
• W2056522147 hasConcept C120665830 @default.
• W2056522147 hasConcept C121332964 @default.
• W2056522147 hasConcept C126322002 @default.
• W2056522147 hasConcept C147483822 @default.
• W2056522147 hasConcept C188280979 @default.
• W2056522147 hasConcept C203014093 @default.
• W2056522147 hasConcept C2522874641 @default.
• W2056522147 hasConcept C2776090121 @default.
• W2056522147 hasConcept C2776409557 @default.
• W2056522147 hasConcept C2777732132 @default.
• W2056522147 hasConcept C2780727368 @default.
• W2056522147 hasConcept C2911091166 @default.
• W2056522147 hasConcept C61511704 @default.
• W2056522147 hasConcept C71924100 @default.
• W2056522147 hasConcept C8891405 @default.
• W2056522147 hasConcept C90924648 @default.
• W2056522147 hasConceptScore W2056522147C120665830 @default.
• W2056522147 hasConceptScore W2056522147C121332964 @default.
• W2056522147 hasConceptScore W2056522147C126322002 @default.
• W2056522147 hasConceptScore W2056522147C147483822 @default.
• W2056522147 hasConceptScore W2056522147C188280979 @default.
• W2056522147 hasConceptScore W2056522147C203014093 @default.
• W2056522147 hasConceptScore W2056522147C2522874641 @default.
• W2056522147 hasConceptScore W2056522147C2776090121 @default.
• W2056522147 hasConceptScore W2056522147C2776409557 @default.
• W2056522147 hasConceptScore W2056522147C2777732132 @default.

• next