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- W2056522305 abstract "Radioiodinated α1 antitrypsin has been found to bind to human lymphocytes. This binding is fast and reversible, and the cells can be saturated. Each lymphocyte can bind a maximum of approximately 1.2 × 106 molecules of α1 antitrypsin with an association constant of 0.7 × 106 M−1×l. The binding is inhibited by the addition of cold α1 antitrypsin or Soybean trypsin inhibitor, and partially by α2 macroglobulin. The data suggest that α1 antitrypsin is likely to bind to a cell surface-associated protease. The addition of cell-free supernatants from lymphocytes incubated at 37°C was found to decrease the binding of α1 antitrypsin, suggesting that the receptor is released from the cell surface." @default.
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- W2056522305 date "1981-02-01" @default.
- W2056522305 modified "2023-10-01" @default.
- W2056522305 title "Binding of alpha 1 antitrypsin (α1 protease inhibitor) to human lymphocytes" @default.
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- W2056522305 doi "https://doi.org/10.1016/0006-291x(81)91171-2" @default.
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